Known targets — ChEMBL curated mechanism
ACHEADRA1AADRA1BADRA1DADRA2AADRA2BADRA2CADRB1ADRB2ADRB3APH1AAPH1BCHRM2CHRM3EZH2GRIN2AHTR1AHTR1BHTR1DHTR1FHTR3ANCSTNP2RY12PSEN1PSEN2PSENENSIGMAR1SLC6A2SLC6A3SLC6A4
The experimentally established mechanism targets of Bromide. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL528404 | 0.97 | — | — | |
| SCHEMBL6670546 | 0.97 | CARM1 (0.33) | — | |
| SCHEMBL25769149 | 0.97 | CARM1 (0.33) | — | |
| Bromide SCHEMBL4361146 | 0.97 | — | — | |
| SCHEMBL1092361 | 0.97 | — | — | |
| Hydrochloric Acid SCHEMBL28745686 | 0.93 | CARM1 (0.32) | — | |
| Hydrochloric Acid SCHEMBL1027109 | 0.93 | CARM1 (0.32) | — | |
| Hydrochloric Acid SCHEMBL28297139 | 0.93 | — | — | |
| SCHEMBL528887 | 0.93 | — | — | |
| SCHEMBL15388363 | 0.93 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20030236229-A1 | Novel 3,5,and/or 6 substituted analogues of swainsonine processes for their preparation and their use as therapeutic agents | GLYCODESIGN INC. (CA) | 2003-12-25 | — | — | US | disclosed |
| US-20020099065-A1 | Novel 3, 5, and/or 6 substituted analogues of swainsonine, processes for their preparation and their use as therapeutic agents | GLYCODESIGN INC. (CA) | 2002-07-25 | — | — | US | disclosed |
| US-6048870-A | MANNOSIDASE INHIBITOR; IMMUNOSTIMULANT | GLYCODESIGN (CA) | 2000-04-11 | — | — | US | disclosed |