Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 1/20 | 0.74 |
| ▸ | MAOB | P27338 | 4/20 | 0.48 |
| ▸ | MAOA | P21397 | 3/20 | 0.48 |
| ▸ | APP | P05067 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.40 |
| ▸ | CA12 | O43570 | 1/20 | 0.40 |
| ▸ | CA2 | P00918 | 1/20 | 0.40 |
| ▸ | CA3 | P07451 | 1/20 | 0.40 |
| ▸ | CA6 | P23280 | 1/20 | 0.40 |
| ▸ | CA9 | Q16790 | 1/20 | 0.40 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.40 |
| ▸ | GABRA1 | P14867 | 2/20 | 0.39 |
| ▸ | GABRG2 | P18507 | 2/20 | 0.39 |
| ▸ | GABRB3 | P28472 | 2/20 | 0.39 |
| ▸ | GABRA5 | P31644 | 2/20 | 0.39 |
| ▸ | GABRA3 | P34903 | 2/20 | 0.39 |
| ▸ | MAPT | P10636 | 2/20 | 0.38 |
| ▸ | XDH | P47989 | 1/20 | 0.38 |
| ▸ | SLC22A12 | Q96S37 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Benzonitrile SCHEMBL30317661 | 1.00 | TSHR (0.74) | TSHRMAOBMAOAAPPALDH1A1 | |
| Benzonitrile SCHEMBL28450139 | 0.97 | TSHR (0.78) | TSHRMAOBMAOAAPPALDH1A1 | |
| Benzonitrile SCHEMBL28179939 | 0.97 | TSHR (0.78) | TSHRMAOBMAOAAPPALDH1A1 | |
| Benzonitrile SCHEMBL14761846 | 0.97 | TSHR (0.78) | TSHRMAOBMAOAAPPALDH1A1 | |
| Benzonitrile SCHEMBL2677758 | 0.97 | TSHR (0.78) | TSHRMAOBMAOAAPPALDH1A1 | |
| Benzonitrile SCHEMBL1021617 | 0.95 | TSHR (0.74) | TSHRMAOBMAOAAPPALDH1A1 | |
| Benzonitrile SCHEMBL16950016 | 0.95 | TSHR (0.74) | TSHRMAOBMAOAAPPALDH1A1 | |
| Benzonitrile SCHEMBL28261821 | 0.92 | TSHR (0.70) | TSHRMAOBMAOAAPPALDH1A1 | |
| Benzonitrile SCHEMBL8355836 | 0.87 | TSHR (0.56) | TSHRMAOBMAOAALDH1A1CYP2A6 | |
| Benzonitrile SCHEMBL3473848 | 0.86 | TSHR (0.88) | TSHRMAOBMAOAAPPALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 20 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-112469737-A | Process for producing hydrogenated nitrile rubber and HNBR compositions thereof | 阿朗新科德国有限责任公司 | 2021-03-09 | — | — | CN | claimed |
| CN-112469737-A | Process for producing hydrogenated nitrile rubber and HNBR compositions thereof | 阿朗新科德国有限责任公司 | 2021-03-09 | — | — | CN | disclosed |
| US-10781270-B2 | Method of production of highly saturated nitrile rubber | ZEON CORPORATION (JP) | 2020-09-22 | — | — | US | disclosed |
| EP-3252084-B1 | METHOD FOR PRODUCING HIGHLY SATURATED NITRILE RUBBER | ZEON CORP (JP) | 2019-08-28 | — | — | EP | disclosed |
| US-20180016360-A1 | METHOD OF PRODUCTION OF HIGHLY SATURATED NITRILE RUBBER | ZEON CORPORATION (JP) | 2018-01-18 | — | — | US | disclosed |
| EP-3252084-A1 | METHOD FOR PRODUCING HIGHLY SATURATED NITRILE RUBBER | Zeon Corporation (JP) | 2017-12-06 | — | — | EP | disclosed |
| EP-2598537-B1 | HYDROGENATION OF DIENE-BASED POLYMERS | ARLANXEO DEUTSCHLAND GMBH (DE) | 2017-05-03 | — | — | EP | disclosed |
| US-9371403-B2 | Hydrogenation of diene-based polymers | LANXESS DEUTSCHLAND GMBH (DE) | 2016-06-21 | — | — | US | disclosed |
| US-9085521-B2 | Catalyst system and process for converting glycerol to lactic acid | UNIVERSITY OF KANSAS (US) | 2015-07-21 | — | — | US | disclosed |
| US-20130331524-A1 | HYDROGENATION OF DIENE-BASED POLYMERS | LANXESS DEUTSCHLAND GMBH (DE) | 2013-12-12 | — | — | US | disclosed |
| EP-2598537-A2 | HYDROGENATION OF DIENE-BASED POLYMERS | Lanxess Deutschland GmbH (DE) | 2013-06-05 | — | — | EP | disclosed |
| US-20120253067-A1 | Catalyst System and Process for Converting Glycerol to Lactic Acid | UNIVERSITY OF KANSAS | 2012-10-04 | — | — | US | disclosed |
| WO-2012013697-A2 | HYDROGENATION OF DIENE-BASED POLYMERS | LANXESS DEUTSCHLAND GMBH (DE) | 2012-02-02 | — | — | WO | disclosed |
| US-7923514-B2 | such as acrylonitrile-butadiene copolymer, using as hydrogenation catalyst a platinum group metal or its compound, and a basic compound | ZEON CORPORATION (JP) | 2011-04-12 | — | — | US | disclosed |
| US-20080132649-A1 | METHOD OF HYDROGENATING CONJUGATED DIENE POLYMER, HYDROGENATION CATALYST SYSTEM, AND COMPOSTION OF BASIC, CONJUGATED DIENE POLYMER | ZEON CORPORATION | 2008-06-05 | — | — | US | disclosed |
| US-20080125556-A1 | Copolymerizing two norbornene monomers, one having a pendant trimethylsilyl or timethylsilylmethyl group, and the other having optional pendant halogen or alkyl groups in the presence of a palladium-based multicomponent catalyst containing palladium, phosphorus, ionic boron and ionic aluminum compounds | JSR CORPORATION (JP) | 2008-05-29 | — | — | US | disclosed |
| US-5169901-A | Catalyzing in presence of high molecular complex of palladium compound and a nitrile grop-containing polymer | NIPPON ZEON CO., LTD. (JP) | 1992-12-08 | — | — | US | disclosed |
| US-5164457-A | Palladium catalyst | NIPPON ZEON CO., LTD. (JP) | 1992-11-17 | — | — | US | disclosed |
| US-5128297-A | Catalysis with palladium compound and acrylonitrile-conjugated diene polymer complex | NIPPON ZEON CO., LTD. (JP) | 1992-07-07 | — | — | US | disclosed |
| US-4451665-A | Process for dimerizing acrylates and methacrylates | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 1984-05-29 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120253067-A1 | Catalyst System and Process for Converting Glycerol to Lactic Acid | GK, LDHA, LIPA | TSHR 3820/4885MAOB 580/4885MAOA 374/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.