Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PRCP | P42785 | 4/20 | 1.00 |
| ▸ | SLC22A1 | O15245 | 1/20 | 1.00 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.66 |
| ▸ | KDM1A | O60341 | 2/20 | 0.54 |
| ▸ | GAA | P10253 | 2/20 | 0.54 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.54 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.54 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.54 |
| ▸ | DRD2 | P14416 | 1/20 | 0.50 |
| ▸ | DRD4 | P21917 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4160731 | 1.00 | PRCP (1.00) | PRCPSLC22A1ADRB2KDM1AGAA | |
| SCHEMBL29768314 | 1.00 | PRCP (1.00) | PRCPSLC22A1ADRB2KDM1AGAA | |
| SCHEMBL5812041 | 1.00 | PRCP (1.00) | PRCPSLC22A1ADRB2KDM1AGAA | |
| Hydrochloric Acid SCHEMBL8823234 | 0.98 | PRCP (0.97) | PRCPSLC22A1ADRB2KDM1AGAA | |
| Water SCHEMBL28203568 | 0.98 | PRCP (0.97) | PRCPSLC22A1ADRB2KDM1AGAA | |
| Urea SCHEMBL28457637 | 0.91 | PRCP (0.83) | PRCPSLC22A1ADRB2KDM1AGAA | |
| SCHEMBL10728169 | 0.87 | PRCP (0.77) | PRCPSLC22A1ADRB2KDM1AGAA | |
| SCHEMBL9411161 | 0.87 | PRCP (0.77) | PRCPSLC22A1ADRB2KDM1AOPRM1 | |
| SCHEMBL10728525 | 0.86 | PRCP (0.74) | PRCPSLC22A1ADRB2KDM1ASMN1; SMN2 | |
| SCHEMBL12859659 | 0.84 | PRCP (0.71) | PRCPSLC22A1KDM4EOPRM1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0154035-B1 | S-TETRAHYDROPROTOBERBERINOXIDASE, PROCESS FOR ITS PREPARATION AND ITS USE | Consortium für elektrochemische Industrie GmbH (DE) | 1990-07-25 | — | — | EP | claimed |
| US-4657861-A | S-tetrahydroprotoberberineoxidase, process for producing the same and use thereof | CONSORTIUM FUR ELEKTROCHEMISCHE INDUSTRIE GMBH (DE) | 1987-04-14 | — | — | US | claimed |
| EP-1866418-A2 | MODULATING PLANT ALKALOIDS | Ceres Inc. (US) | 2007-12-19 | — | — | EP | disclosed |
| WO-2006113481-A1 | SECONDARY METABOLITE PRODUCTION VIA MANIPULATION OF GENOME METHYLATION | CERES INC. (US) | 2006-10-26 | — | — | WO | disclosed |
| WO-2006091676-A2 | MODULATING PLANT ALKALOIDS | CERES INC. (US) | 2006-08-31 | — | — | WO | disclosed |
| EP-0154035-B1 | S-TETRAHYDROPROTOBERBERINOXIDASE, PROCESS FOR ITS PREPARATION AND ITS USE | Consortium für elektrochemische Industrie GmbH (DE) | 1990-07-25 | — | — | EP | disclosed |
| US-4657861-A | S-tetrahydroprotoberberineoxidase, process for producing the same and use thereof | CONSORTIUM FUR ELEKTROCHEMISCHE INDUSTRIE GMBH (DE) | 1987-04-14 | — | — | US | disclosed |
| US-4657861-A | S-tetrahydroprotoberberineoxidase, process for producing the same and use thereof | CONSORTIUM FUR ELEKTROCHEMISCHE INDUSTRIE GMBH (DE) | 1987-04-14 | — | — | US | disclosed |
| EP-0154035-A2 | S-tetrahydroprotoberberinoxidase, process for its preparation and its use | Consortium für elektrochemische Industrie GmbH (DE) | 1985-09-11 | — | — | EP | disclosed |
| EP-0154035-A2 | S-tetrahydroprotoberberinoxidase, process for its preparation and its use | Consortium für elektrochemische Industrie GmbH (DE) | 1985-09-11 | — | — | EP | disclosed |