Known targets — ChEMBL curated mechanism
MMP1MMP13MMP7MMP8polrplArplBrplCrplDrplErplFrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmFrpmGrpmHrpmIrpmJrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUykgMykgO
The experimentally established mechanism targets of Alcohol. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPHX1 | P07099 | 10/20 | 0.42 |
| ▸ | LMNA | P02545 | 2/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
| ▸ | TSHR | P16473 | 2/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | NAAA | Q02083 | 1/20 | 0.39 |
| ▸ | ADH1B | P00325 | 1/20 | 0.38 |
| ▸ | ADH1C | P00326 | 1/20 | 0.38 |
| ▸ | ADH1A | P07327 | 1/20 | 0.38 |
| ▸ | ADH4 | P08319 | 1/20 | 0.38 |
| ▸ | ADH7 | P40394 | 1/20 | 0.38 |
| ▸ | GBA1 | P04062 | 2/20 | 0.38 |
| ▸ | CASP2 | P42575 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7565741 | 0.95 | EPHX1 (0.46) | EPHX1ALDH1A1TSHRADH1BADH1C | |
| SCHEMBL28415018 | 0.95 | EPHX1 (0.46) | EPHX1ALDH1A1TSHRADH1BADH1C | |
| SCHEMBL27736677 | 0.95 | EPHX1 (0.46) | EPHX1ALDH1A1TSHRADH1BADH1C | |
| SCHEMBL28119153 | 0.95 | EPHX1 (0.46) | EPHX1ALDH1A1TSHRADH1BADH1C | |
| SCHEMBL28120308 | 0.93 | ALDH1A1 (0.46) | EPHX1ALDH1A1TSHRADH1BADH1C | |
| SCHEMBL339968 | 0.85 | — | — | |
| SCHEMBL28515220 | 0.81 | TDP1 (0.44) | LMNAALDH1A1TSHRHSD17B10MEN1 | |
| SCHEMBL8073294 | 0.81 | EPHX1 (0.46) | EPHX1ALDH1A1TSHRADH1BADH1C | |
| SCHEMBL76225 | 0.81 | EPHX1 (0.46) | EPHX1ALDH1A1TSHRADH1BADH1C | |
| SCHEMBL10980330 | 0.81 | EPHX1 (0.46) | EPHX1ALDH1A1TSHRADH1BADH1C |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1864187-A1 | FLAME-RETARDANT COMPOSITION FOR SOLDER RESIST AND CURED PRODUCT THEREOF | SHOWA DENKO KABUSHIKI KAISHA (JP) | 2007-12-12 | — | — | EP | disclosed |
| WO-2006106892-A1 | FLAME-RETARDANT COMPOSITION FOR SOLDER RESIST AND CURED PRODUCT THEREOF | SHOWA DENKO K.K. (JP) | 2006-10-12 | — | — | WO | disclosed |