SCHEMBL5284230

SCHEMBL5284230

CCC(C)CC1(CC(C)CC)c2cc(CCCc3ccc(-c4nc(-c5ccc(CCCc6ccc7c(c6)C(CC(C)CC)(CC(C)CC)c6cc([Si](C)(C)C)ccc6-7)cc5)nc(-c5ccc(CCCc6ccc7c(c6)C(CC(C)CC)(CC(C)CC)c6cc([Si](C)(C)C)ccc6-7)cc5)n4)cc3)ccc2-c2ccc([Si](C)(C)C)cc21

nearest known ligand 0.31

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
ATM Q13315 1/20 0.30
TDP1 Q9NUW8 1/20 0.30
L3MBTL1 Q9Y468 1/20 0.30
NPC1 O15118 1/20 0.30
ALDH1A1 P00352 1/20 0.30
MAPT P10636 1/20 0.30
NFKB1 P19838 1/20 0.30
S1PR1 P21453 1/20 0.30
RAB9A P51151 1/20 0.30
NFKB2 Q00653 1/20 0.30
RELA Q04206 1/20 0.30
SMN1; SMN2 Q16637 1/20 0.30
NPSR1 Q6W5P4 1/20 0.30
SPHK2 Q9NRA0 1/20 0.30
SPHK1 Q9NYA1 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5322370 0.87 NPC1 (0.31) NPC1NFKB1RAB9ANFKB2RELA
SCHEMBL5418620 0.86
SCHEMBL5284227 0.79
SCHEMBL5283014 0.77 ALDH1A1 (0.33) ALDH1A1MAPTNPSR1
SCHEMBL5502525 0.75
SCHEMBL5501884 0.74 PDK2 (0.32)
SCHEMBL5498380 0.74 PDK2 (0.32)
SCHEMBL5663449 0.74
SCHEMBL5498910 0.72
SCHEMBL5498599 0.72 PDK2 (0.32)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20070111027-A1 Light-emitting organic materials NATIONAL SCIENCE FOUNDATION 2007-05-17 US disclosed
WO-2007016454-A2 LIGHT-EMITTING ORGANIC MATERIALS UNIVERSITY OF ROCHESTER (US) 2007-02-08 WO disclosed