Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 1/20 | 0.49 |
| ▸ | GAA | P10253 | 2/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.47 |
| ▸ | MEN1 | O00255 | 3/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.47 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4708188 | 0.75 | HTT (0.47) | — | |
| SCHEMBL466479 | 0.74 | — | — | |
| SCHEMBL4234238 | 0.73 | HTT (0.50) | LMNA | |
| SCHEMBL1574233 | 0.73 | HTT (0.50) | LMNA | |
| Hydrochloric Acid SCHEMBL4598483 | 0.72 | HTT (0.49) | — | |
| Hydrochloric Acid SCHEMBL4597452 | 0.72 | HTT (0.49) | — | |
| Hydrochloric Acid SCHEMBL4598525 | 0.72 | HTT (0.49) | — | |
| SCHEMBL7527727 | 0.72 | — | — | |
| SCHEMBL2998081 | 0.72 | — | — | |
| SCHEMBL169064 | 0.72 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007009699-A2 | USE OF SUBSTITUTED PYRAZOLINE COMPOUNDS AND THEIR DERIVATIVES FOR THE TREATMENT OF CANNABINOID SYSTEM-ASSOCIATED DISEASES | LABORATORIOS DEL DR. ESTEVE, S.A (ES) | 2007-01-25 | — | — | WO | claimed |