Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOB | P27338 | 1/20 | 0.44 |
| ▸ | GABRB3 | P28472 | 8/20 | 0.42 |
| ▸ | GABRA2 | P47869 | 2/20 | 0.32 |
| ▸ | GABRB2 | P47870 | 2/20 | 0.32 |
| ▸ | GAA | P10253 | 1/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | TSHR | P16473 | 1/20 | 0.31 |
| ▸ | HTT | P42858 | 1/20 | 0.31 |
| ▸ | MAOA | P21397 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5277670 | 0.89 | MAOB (0.45) | MAOBGABRB3GABRA2GABRB2MAOA | |
| SCHEMBL5277438 | 0.88 | MAOB (0.56) | MAOBGABRB3GABRA2GABRB2MAOA | |
| SCHEMBL24349128 | 0.86 | MAOB (0.51) | MAOBGABRB3ALDH1A1 | |
| SCHEMBL5284450 | 0.84 | GABRB3 (0.38) | MAOBGABRB3GABRA2GABRB2GAA | |
| SCHEMBL5282328 | 0.83 | MAOB (0.53) | MAOBGABRB3GABRA2GABRB2ALDH1A1 | |
| SCHEMBL5275084 | 0.83 | GABRB3 (0.42) | MAOBGABRB3GABRA2GABRB2MAOA | |
| SCHEMBL5278092 | 0.80 | MAOB (0.40) | MAOBGABRB3 | |
| SCHEMBL5283581 | 0.80 | MAOB (0.40) | MAOBGABRB3GABRA2GABRB2 | |
| SCHEMBL5278533 | 0.79 | GABRB3 (0.40) | GABRB3GABRA2GABRB2ALDH1A1 | |
| SCHEMBL5275616 | 0.79 | MAOB (0.56) | MAOBGABRB3GABRA2GABRB2KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3154997-B1 | AURISTATIN DERIVATIVES AND CONJUGATES THEREOF | NOVARTIS AG (CH) | 2020-02-19 | — | — | EP | disclosed |
| EP-1859781-A2 | Brightening and/or colouring agent with triazoles | Henkel Kommanditgesellschaft auf Aktien (DE) | 2007-11-28 | — | — | EP | disclosed |