SCHEMBL5284542

SCHEMBL5284542

CCCn1nnc(C(Cl)(Cl)Cl)c1C(Cl)(Cl)Cl

nearest known ligand 0.37

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
SLC9A1 P19634 1/20 0.37
ALDH1A1 P00352 2/20 0.33
CYP1A2 P05177 2/20 0.33
GRM2 Q14416 1/20 0.33
TOP2A P11388 1/20 0.32
ADORA2A P29274 1/20 0.31
ADORA2B P29275 1/20 0.31
GRIA4 P48058 1/20 0.30
HCAR3 P49019 1/20 0.30
MEN1 O00255 1/20 0.30
CYP2C9 P11712 1/20 0.30
CYP2C19 P33261 1/20 0.30
KMT2A Q03164 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5279834 0.89 SLC9A1 (0.40) SLC9A1GRM2TOP2AHCAR3MEN1
SCHEMBL5277720 0.89 SLC9A1 (0.35) SLC9A1ALDH1A1CYP1A2GRM2TOP2A
SCHEMBL5283596 0.89 SLC9A1 (0.35) SLC9A1ALDH1A1CYP1A2GRM2TOP2A
SCHEMBL5273417 0.87 SLC9A1 (0.34) SLC9A1ALDH1A1CYP1A2GRM2
SCHEMBL5281406 0.87 SLC9A1 (0.34) SLC9A1ALDH1A1CYP1A2GRM2
SCHEMBL5277843 0.87 SLC9A1 (0.34) SLC9A1ALDH1A1CYP1A2GRM2
SCHEMBL5283630 0.87 SLC9A1 (0.34) SLC9A1ALDH1A1CYP1A2GRM2
SCHEMBL5280258 0.86 SLC9A1 (0.43) SLC9A1ALDH1A1GRM2TOP2AHCAR3
SCHEMBL5281103 0.84 SLC9A1 (0.33) SLC9A1
SCHEMBL5283702 0.84 SLC9A1 (0.33) SLC9A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1859781-A2 Brightening and/or colouring agent with triazoles Henkel Kommanditgesellschaft auf Aktien (DE) 2007-11-28 EP disclosed