SCHEMBL5284644

SCHEMBL5284644

CNS(=O)(=O)NS(=O)(=O)c1ccc(N)cc1

nearest known ligand 0.53

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CA1 P00915 6/20 0.53
CA2 P00918 6/20 0.53
MMP1 P03956 1/20 0.53
MMP2 P08253 1/20 0.53
MMP9 P14780 1/20 0.53
MMP8 P22894 1/20 0.53
MMP13 P45452 1/20 0.53
TSHR P16473 2/20 0.52
SMN1; SMN2 Q16637 2/20 0.52
DHFR P00374 1/20 0.52
TDP1 Q9NUW8 1/20 0.52
HTR6 P50406 4/20 0.51
CA9 Q16790 6/20 0.50
CA12 O43570 4/20 0.50
ALDH1A1 P00352 1/20 0.47
CYP3A4 P08684 2/20 0.47
KMT2A Q03164 1/20 0.47
LMNA P02545 1/20 0.46
MPO P05164 1/20 0.46
CYP2C9 P11712 1/20 0.46

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL687206 0.83 SMN1; SMN2 (0.64) CA1CA2MMP1MMP2MMP9
SCHEMBL31520571 0.83 SMN1; SMN2 (0.64) CA1CA2MMP1MMP2MMP9
SCHEMBL153130 0.83 CA1 (0.67) CA1CA2MMP1MMP2MMP9
Hydrochloric Acid SCHEMBL5344901 0.81 SMN1; SMN2 (0.61) CA1CA2MMP1MMP2MMP9
SCHEMBL4250009 0.79 CA1 (0.57) CA1CA2MMP1MMP2MMP9
SCHEMBL8564462 0.75 KMT2A (0.66) CA1CA2MMP1MMP2MMP9
SCHEMBL11760454 0.74 CA1 (0.53) CA1CA2MMP1MMP2MMP9
SCHEMBL22800554 0.73 CA1 (0.55) CA1CA2MMP1MMP2MMP9
SCHEMBL16789545 0.73 CA1 (0.50) CA1CA2MMP1MMP2MMP9
SCHEMBL11245748 0.73 SMN1; SMN2 (0.81) CA1CA2MMP1MMP2MMP9

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2007002780-A2 TOPICAL PRESERVATIVE COMPOSITIONS BAUSCH & LOMB INCORPORATED (US) 2007-01-04 WO disclosed