Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPHX2 | P34913 | 5/20 | 0.70 |
| ▸ | KDM5A | P29375 | 7/20 | 0.54 |
| ▸ | KDM4C | Q9H3R0 | 7/20 | 0.54 |
| ▸ | PHF8 | Q9UPP1 | 4/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.52 |
| ▸ | KDM5C | P41229 | 1/20 | 0.51 |
| ▸ | KDM5B | Q9UGL1 | 1/20 | 0.51 |
| ▸ | CNR1 | P21554 | 1/20 | 0.51 |
| ▸ | BCHE | P06276 | 1/20 | 0.51 |
| ▸ | ACHE | P22303 | 1/20 | 0.51 |
| ▸ | CES2 | O00748 | 3/20 | 0.50 |
| ▸ | CES1 | P23141 | 3/20 | 0.50 |
| ▸ | KDM4A | O75164 | 2/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11777140 | 1.00 | EPHX2 (0.70) | EPHX2KDM5AKDM4CPHF8ALDH1A1 | |
| SCHEMBL2483891 | 1.00 | EPHX2 (0.70) | EPHX2KDM5AKDM4CPHF8ALDH1A1 | |
| SCHEMBL11702777 | 1.00 | EPHX2 (0.70) | EPHX2KDM5AKDM4CPHF8ALDH1A1 | |
| SCHEMBL2482309 | 1.00 | EPHX2 (0.70) | EPHX2KDM5AKDM4CPHF8ALDH1A1 | |
| SCHEMBL5293678 | 1.00 | EPHX2 (0.70) | EPHX2KDM5AKDM4CPHF8ALDH1A1 | |
| SCHEMBL2484953 | 1.00 | EPHX2 (0.70) | EPHX2KDM5AKDM4CPHF8ALDH1A1 | |
| SCHEMBL23343387 | 1.00 | EPHX2 (0.70) | EPHX2KDM5AKDM4CPHF8ALDH1A1 | |
| SCHEMBL11775303 | 1.00 | EPHX2 (0.70) | EPHX2KDM5AKDM4CPHF8ALDH1A1 | |
| SCHEMBL21596652 | 1.00 | EPHX2 (0.70) | EPHX2KDM5AKDM4CPHF8ALDH1A1 | |
| SCHEMBL28514548 | 1.00 | EPHX2 (0.70) | EPHX2KDM5AKDM4CPHF8ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007005887-A2 | ANDROGEN RECEPTOR MODULATOR COMPOUNDS, COMPOSITIONS AND USES THEREOF | LIGAND PHARMACEUTICALS INCORPORATED (US) | 2007-01-11 | — | — | WO | disclosed |