Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A9 | P48067 | 18/20 | 0.64 |
| ▸ | HTR6 | P50406 | 1/20 | 0.43 |
| ▸ | PREP | P48147 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5240941 | 0.89 | SLC6A9 (0.50) | SLC6A9 | |
| SCHEMBL5242247 | 0.89 | SLC6A9 (0.69) | SLC6A9 | |
| SCHEMBL5245456 | 0.89 | SLC6A9 (0.69) | SLC6A9 | |
| SCHEMBL5243172 | 0.88 | SLC6A9 (0.51) | SLC6A9PREP | |
| SCHEMBL5242939 | 0.85 | SLC6A9 (0.68) | SLC6A9PREP | |
| SCHEMBL5273842 | 0.85 | SLC6A9 (0.68) | SLC6A9PREP | |
| SCHEMBL5281363 | 0.85 | SLC6A9 (0.68) | SLC6A9PREP | |
| SCHEMBL5242556 | 0.84 | SLC6A9 (0.70) | SLC6A9PREP | |
| SCHEMBL5241374 | 0.84 | SLC6A9 (0.70) | SLC6A9PREP | |
| SCHEMBL5241891 | 0.84 | SLC6A9 (0.70) | SLC6A9PREP |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1455777-B1 | GLYT1 TRANSPORTER INHIBITORS AND USES THEREOF IN TREATMENT OF NEUROLOGICAL AND NEUROPSYCHIATRIC DISORDERS | SMITHKLINE BEECHAM PLC (GB) | 2007-11-21 | — | — | EP | claimed |