Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 3/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.52 |
| ▸ | MAPT | P10636 | 4/20 | 0.51 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.48 |
| ▸ | LMNA | P02545 | 4/20 | 0.48 |
| ▸ | POLB | P06746 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.47 |
| ▸ | HPGD | P15428 | 1/20 | 0.47 |
| ▸ | F2R | P25116 | 1/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.47 |
| ▸ | NPC1 | O15118 | 2/20 | 0.47 |
| ▸ | RAB9A | P51151 | 2/20 | 0.47 |
| ▸ | TP53 | P04637 | 1/20 | 0.47 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.47 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.47 |
| ▸ | RELA | Q04206 | 1/20 | 0.47 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.46 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.46 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL528847 | 0.91 | MEN1 (0.55) | MEN1KMT2AMAPTNPSR1LMNA | |
| SCHEMBL528484 | 0.90 | MEN1 (0.48) | MEN1KMT2AMAPTNPSR1LMNA | |
| SCHEMBL529730 | 0.90 | MAPT (0.58) | MEN1KMT2AMAPTNPSR1LMNA | |
| SCHEMBL528321 | 0.90 | MEN1 (0.48) | MEN1KMT2AMAPTNPSR1LMNA | |
| SCHEMBL528589 | 0.88 | MEN1 (0.52) | MEN1KMT2AMAPTNPSR1LMNA | |
| SCHEMBL528261 | 0.87 | MAPK1 (0.58) | MEN1KMT2AMAPTNPSR1POLB | |
| SCHEMBL529102 | 0.86 | MAPT (0.55) | MEN1KMT2AMAPTNPSR1LMNA | |
| SCHEMBL528112 | 0.86 | KMT2A (0.70) | MEN1KMT2AMAPTNPSR1LMNA | |
| SCHEMBL529028 | 0.86 | MEN1 (0.50) | MEN1KMT2AMAPTNPSR1LMNA | |
| SCHEMBL528567 | 0.85 | KCNK3 (0.54) | MEN1KMT2AMAPTNPSR1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012014127-A1 | 5-LIPOXYGENASE INHIBITORS | RANBAXY LABORATORIES LIMITED (IN) | 2012-02-02 | — | — | WO | disclosed |