Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK1 | P28482 | 2/20 | 0.58 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.58 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.55 |
| ▸ | KCNK3 | O14649 | 7/20 | 0.54 |
| ▸ | KCNK9 | Q9NPC2 | 7/20 | 0.54 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.54 |
| ▸ | POLB | P06746 | 1/20 | 0.54 |
| ▸ | MEN1 | O00255 | 2/20 | 0.51 |
| ▸ | MAPT | P10636 | 3/20 | 0.50 |
| ▸ | HTT | P42858 | 1/20 | 0.50 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.50 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.47 |
| ▸ | GAA | P10253 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL529422 | 0.93 | NPC1 (0.53) | MAPK1KDM4EL3MBTL1KCNK3KCNK9 | |
| SCHEMBL528474 | 0.91 | KCNK3 (0.53) | MAPK1KDM4EL3MBTL1KCNK3KCNK9 | |
| SCHEMBL528468 | 0.90 | L3MBTL1 (0.57) | MAPK1KDM4EL3MBTL1KCNK3KCNK9 | |
| SCHEMBL528632 | 0.90 | ALDH1A1 (0.51) | MAPK1KDM4EL3MBTL1KCNK3KCNK9 | |
| SCHEMBL528847 | 0.89 | MEN1 (0.55) | KDM4EL3MBTL1KCNK3KCNK9KMT2A | |
| SCHEMBL529458 | 0.89 | MAPT (0.52) | MAPK1KDM4EL3MBTL1KMT2APOLB | |
| SCHEMBL528567 | 0.89 | KCNK3 (0.54) | MAPK1KDM4EL3MBTL1KCNK3KCNK9 | |
| SCHEMBL528522 | 0.87 | MEN1 (0.52) | KDM4EL3MBTL1KMT2APOLBMEN1 | |
| SCHEMBL528589 | 0.87 | MEN1 (0.52) | KDM4EL3MBTL1KCNK3KCNK9KMT2A | |
| SCHEMBL529102 | 0.86 | MAPT (0.55) | KDM4EKMT2APOLBMEN1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012014127-A1 | 5-LIPOXYGENASE INHIBITORS | RANBAXY LABORATORIES LIMITED (IN) | 2012-02-02 | — | — | WO | disclosed |