Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.39 |
| ▸ | LMNA | P02545 | 3/20 | 0.39 |
| ▸ | MAPT | P10636 | 4/20 | 0.38 |
| ▸ | THRB | P10828 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 3/20 | 0.37 |
| ▸ | HTT | P42858 | 2/20 | 0.37 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | TTR | P02766 | 1/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.35 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.35 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.35 |
| ▸ | RECQL | P46063 | 1/20 | 0.35 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4707290 | 0.83 | ALDH1A1 (0.41) | ALDH1A1KMT2ALMNAMAPTTHRB | |
| SCHEMBL4704819 | 0.83 | ALDH1A1 (0.37) | ALDH1A1KMT2ALMNAMAPTTHRB | |
| SCHEMBL5289445 | 0.81 | ALDH1A1 (0.38) | ALDH1A1KMT2ALMNAMAPTTHRB | |
| SCHEMBL7815081 | 0.80 | ALDH1A1 (0.59) | ALDH1A1KMT2ALMNAMAPTTHRB | |
| SCHEMBL20328809 | 0.78 | LRRK2 (0.40) | ALDH1A1KMT2ALMNAMAPTTHRB | |
| SCHEMBL31639655 | 0.78 | ALDH1A1 (0.38) | ALDH1A1KMT2ALMNAMAPTTHRB | |
| SCHEMBL5287503 | 0.76 | SOS1 (0.31) | — | |
| SCHEMBL3039837 | 0.76 | ALDH1A1 (0.43) | ALDH1A1KMT2ALMNAMAPTTHRB | |
| SCHEMBL28196822 | 0.76 | ALDH1A1 (0.46) | ALDH1A1KMT2ALMNAMAPTHTT | |
| Hydrochloric Acid SCHEMBL5292108 | 0.76 | ALDH1A1 (0.36) | ALDH1A1KMT2ALMNAMAPTTHRB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007004049-A1 | OXAZOLIDINONES CONTAINING AZETIDINE AS ANTIBACTERIAL AGENTS | PHARMACIA & UPJOHN COMPANY LLC (US) | 2007-01-11 | — | — | WO | disclosed |