Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 10/20 | 0.37 |
| ▸ | PTGS1 | P23219 | 5/20 | 0.35 |
| ▸ | PTGS2 | P35354 | 5/20 | 0.35 |
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.34 |
| ▸ | NPC1 | O15118 | 4/20 | 0.33 |
| ▸ | RAB9A | P51151 | 4/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.33 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 3/20 | 0.33 |
| ▸ | CXCR1 | P25024 | 2/20 | 0.33 |
| ▸ | CXCR2 | P25025 | 2/20 | 0.33 |
| ▸ | LMNA | P02545 | 2/20 | 0.33 |
| ▸ | HPGD | P15428 | 2/20 | 0.33 |
| ▸ | RECQL | P46063 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.33 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.33 |
| ▸ | SLC22A6 | Q4U2R8 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2402694 | 0.82 | EPHX1 (0.33) | SMN1; SMN2ALDH1A1NPC1RAB9ACYP1A2 | |
| SCHEMBL30843547 | 0.81 | AKR1C3 (0.36) | SMN1; SMN2HCAR2ALDH1A1NPC1RAB9A | |
| SCHEMBL20231997 | 0.81 | AKR1C3 (0.36) | SMN1; SMN2HCAR2ALDH1A1NPC1RAB9A | |
| SCHEMBL434029 | 0.80 | HCAR2 (0.52) | SMN1; SMN2HCAR2ALDH1A1NPC1RAB9A | |
| SCHEMBL2400000 | 0.79 | SMN1; SMN2 (0.37) | SMN1; SMN2ALDH1A1NPC1RAB9ACYP1A2 | |
| SCHEMBL10720484 | 0.78 | SMN1; SMN2 (0.39) | SMN1; SMN2PTGS1PTGS2HCAR2ALDH1A1 | |
| Ibotenic Acid SCHEMBL28147541 | 0.78 | GRM1 (0.39) | SMN1; SMN2ALDH1A1CYP1A2CYP2C19LMNA | |
| Ibotenic Acid SCHEMBL28147540 | 0.78 | GRM1 (0.39) | SMN1; SMN2ALDH1A1CYP1A2CYP2C19LMNA | |
| Ibotenic Acid SCHEMBL4582627 | 0.76 | GRM1 (0.43) | ALDH1A1CYP1A2CYP2C19LMNAHPGD | |
| Ibotenic Acid SCHEMBL15732748 | 0.76 | GRM1 (0.43) | ALDH1A1CYP1A2CYP2C19LMNAHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007002594-A1 | COSMETIC COMPOSITIONS AND METHODS USING TRANSFORMING GROWTH FACTOR-BETA MIMICS | BHATNAGAR RAJENDRA S (US) | 2007-01-04 | — | — | WO | disclosed |