Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 6/20 | 0.67 |
| ▸ | HSD17B10 | Q99714 | 6/20 | 0.67 |
| ▸ | HIF1A | Q16665 | 5/20 | 0.67 |
| ▸ | MAPK1 | P28482 | 4/20 | 0.67 |
| ▸ | ALOX15 | P16050 | 3/20 | 0.67 |
| ▸ | THPO | P40225 | 3/20 | 0.67 |
| ▸ | TSHR | P16473 | 3/20 | 0.67 |
| ▸ | NFKB1 | P19838 | 3/20 | 0.67 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.67 |
| ▸ | TP53 | P04637 | 2/20 | 0.67 |
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.65 |
| ▸ | LMNA | P02545 | 4/20 | 0.65 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.65 |
| ▸ | HPGD | P15428 | 2/20 | 0.65 |
| ▸ | BLM | P54132 | 2/20 | 0.65 |
| ▸ | GMNN | O75496 | 2/20 | 0.65 |
| ▸ | PMP22 | Q01453 | 2/20 | 0.65 |
| ▸ | GFER | P55789 | 1/20 | 0.65 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.65 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.65 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30674028 | 1.00 | MAPT (0.67) | MAPTHSD17B10HIF1AMAPK1ALOX15 | |
| Bromide SCHEMBL9444692 | 0.98 | MAPT (0.65) | MAPTHSD17B10HIF1AMAPK1ALOX15 | |
| SCHEMBL11806768 | 0.88 | DRD1 (0.71) | MAPTHSD17B10HIF1AMAPK1ALOX15 | |
| SCHEMBL30088530 | 0.88 | DRD1 (0.71) | MAPTHSD17B10HIF1AMAPK1ALOX15 | |
| SCHEMBL9503350 | 0.87 | MAPT (0.65) | MAPTHSD17B10HIF1AMAPK1ALOX15 | |
| Bromide SCHEMBL11805167 | 0.86 | DRD1 (0.69) | MAPTHSD17B10HIF1AMAPK1ALOX15 | |
| SCHEMBL11566078 | 0.84 | MAPT (0.47) | MAPTHSD17B10HIF1AMAPK1ALOX15 | |
| SCHEMBL28565282 | 0.84 | DRD1 (0.67) | MAPTHSD17B10HIF1AMAPK1ALOX15 | |
| SCHEMBL107292 | 0.82 | MAPT (0.63) | MAPTHSD17B10HIF1AMAPK1ALOX15 | |
| SCHEMBL11074753 | 0.82 | MAPT (0.63) | MAPTHSD17B10HIF1AMAPK1ALOX15 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-112094375-A | Adhesive hydrogel and self-adhesive medical mask and preparation method thereof | 四川大学华西医院 | 2020-12-18 | — | — | CN | claimed |
| WO-2007016214-A2 | METHOD FOR INHIBITING TNF-ALPHA | CARITAS ST. ELIZABETH'S MEDICAL CENTER (US) | 2007-02-08 | — | — | WO | claimed |
| WO-2023028350-A1 | THERAPEUTIC COMPOSITIONS AND RELATED METHODS | BOYCE THOMPSON INSTITUTE FOR PLANT RESEARCH, INC. (US) | 2023-03-02 | — | — | WO | disclosed |
| CN-112094375-A | Adhesive hydrogel and self-adhesive medical mask and preparation method thereof | 四川大学华西医院 | 2020-12-18 | — | — | CN | disclosed |
| US-20100137903-A1 | BIOADHESIVE CONSTRUCTS | NERITES CORPORATION (US) | 2010-06-03 | — | — | US | disclosed |
| US-20090292119-A1 | METHODS FOR SYNTHESIZING BENZOTHIAZEPINE COMPOUNDS | THE TRUSTEES OF COLUMBIA UNIVERSITY IN THE CITY OF NEW YORK (US) | 2009-11-26 | — | — | US | disclosed |
| WO-2008092257-A1 | USE OF CATECHOLAMINES AND RELATED COMPOUNDS AS ANTI-ANGIOGENIC AGENTS | NATIONAL RESEARCH COUNCIL OF CANADA (CA) | 2008-08-07 | — | — | WO | disclosed |
| EP-1326523-A4 | IMAGING OF ENZYMATIC ACTIVITY | GEN HOSPITAL CORP (US) | 2005-01-05 | — | — | EP | disclosed |
| EP-1326523-A2 | IMAGING OF ENZYMATIC ACTIVITY | THE GENERAL HOSPITAL CORPORATION (US) | 2003-07-16 | — | — | EP | disclosed |
| WO-2002032291-A2 | IMAGING OF ENZYMATIC ACTIVITY | THE GENERAL HOSPITAL CORPORATION (US) | 2002-04-25 | — | — | WO | disclosed |
| WO-1994000432-A1 | ANORECTIC EPINEPHRINE DERIVATIVES | THE UNITED STATES OF AMERICA, REPRESENTED BY THE SECRETARY, DEPARTMENT OF HEALTH AND HUMAN SERVICES (US) | 1994-01-06 | — | — | WO | disclosed |
| US-5246949-A | And lactic acid esters, treatment of hypotension and cardiac circulatory insufficiency | SANSHO CO., LTD. (JP) | 1993-09-21 | — | — | US | disclosed |
| US-4218470-A | CARDIOCIRCULATORY ANALEPTICS | SIMES SOCIETA ITALIANA MEDICINALI E SINTETICI S.P.A. (IT) | 1980-08-19 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090292119-A1 | METHODS FOR SYNTHESIZING BENZOTHIAZEPINE COMPOUNDS | KCNB2, KCNJ2, KCNJ5 | MAPT 1124/4885HSD17B10 345/4885HIF1A 3645/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.