SCHEMBL5286338

SCHEMBL5286338

N=C(N)c1ccccc1OCCCCCCOc1ccccc1C(=N)N

nearest known ligand 0.58

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
LMNA P02545 2/20 0.58
CHRM2 P08172 2/20 0.58
ADRA2A P08913 2/20 0.58
SLC6A3 Q01959 2/20 0.58
MEN1 O00255 1/20 0.58
NR1I2 O75469 1/20 0.58
CYP3A4 P08684 1/20 0.58
MAPT P10636 1/20 0.58
OPRK1 P41145 1/20 0.58
HTR2B P41595 1/20 0.58
KMT2A Q03164 1/20 0.58
HDAC6 Q9UBN7 1/20 0.58
SMN1; SMN2 Q16637 1/20 0.51
PRSS1 P07477 5/20 0.49
PRMT1 Q99873 3/20 0.47
F2 P00734 2/20 0.47
ST14 Q9Y5Y6 2/20 0.47
PLAU P00749 1/20 0.47
PRMT5 O14744 1/20 0.47
SLC22A2 O15244 1/20 0.47

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9857038 0.94 LMNA (0.51) LMNACHRM2ADRA2ASLC6A3MEN1
SCHEMBL17275051 0.92 LMNA (0.72) LMNACHRM2ADRA2ASLC6A3MEN1
SCHEMBL29111040 0.92 LMNA (0.72) LMNACHRM2ADRA2ASLC6A3MEN1
SCHEMBL2565211 0.92 LMNA (0.72) LMNACHRM2ADRA2ASLC6A3MEN1
Hydrochloric Acid SCHEMBL8780381 0.90 LMNA (0.70) LMNACHRM2ADRA2ASLC6A3MEN1
SCHEMBL27603253 0.90 LMNA (0.69) LMNACHRM2ADRA2ASLC6A3MEN1
SCHEMBL31467536 0.87 LMNA (0.46) LMNACHRM2ADRA2ASLC6A3MEN1
SCHEMBL2560081 0.87 LMNA (0.62) LMNACHRM2ADRA2ASLC6A3MEN1
SCHEMBL2566314 0.86 LMNA (0.50) LMNACHRM2ADRA2ASLC6A3MEN1
Hydrochloric Acid SCHEMBL11625882 0.86 LMNA (0.60) LMNACHRM2ADRA2ASLC6A3MEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 15 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3687497-A1 TOPICAL COMPOSITION AND METHOD FOR TREATING AND PREVENTING ATOPIC DERMATITIS AND INFECTIONS RELATED TO BACTERIA BIOFILM Johnson & Johnson Consumer Inc. (US) 2020-08-05 EP disclosed
WO-2019064162-A1 TOPICAL COMPOSITION AND METHOD FOR TREATING AND PREVENTING ATOPIC DERMATITIS AND INFECTIONS RELATED TO BACTERIA BIOFILM JOHNSON & JOHNSON CONSUMER INC. (US) 2019-04-04 WO disclosed
US-20180339166-A1 DELIVERY OF LARGE MOLECULAR WEIGHT BIOLOGICALLY ACTIVE SUBSTANCES PhotoKinetix Holdings, Inc. (US) 2018-11-29 US disclosed
US-20170080247-A1 DELIVERY OF LARGE MOLECULAR WEIGHT BIOLOGICALLY ACTIVE SUBSTANCES PhotoKinetix Holdings, Inc. (US) 2017-03-23 US disclosed
US-9474911-B2 Delivery of large molecular weight biologically active substances PHOTOKINETIX HOLDINGS INC. (US) 2016-10-25 US disclosed
US-20140261517-A1 COMPOSITIONS AND METHODS FOR TREATING KERATIN BASED FIBERS COOLWAY INC. (US) 2014-09-18 US disclosed
US-20140128798-A1 DELIVERY OF LARGE MOLECULAR WEIGHT BIOLOGICALLY ACTIVE SUBSTANCES PHOTOKINETIX HOLDINGS INC. (US) 2014-05-08 US disclosed
EP-2720671-A1 TRANSLUCENT AND SYRUPY COSMETIC COMPOSITION Chanel Parfums Beauté (FR) 2014-04-23 EP disclosed
WO-2012172425-A1 TRANSLUCENT AND SYRUPY COSMETIC COMPOSITION CHANEL PARFUMS BEAUTE (FR) 2012-12-20 WO disclosed
EP-1858463-A1 ABSORBENT ARTICLE HAVING BARRIER SHEET AGAINST THE TRANSFER OF THE SKIN CARE COMPOSITION The Procter and Gamble Company (US) 2007-11-28 EP disclosed
EP-1848392-A1 SANITARY NAPKINS CAPABLE OF TAKING COMPLEX THREE-DIMENSIONAL SHAPE IN USE The Procter and Gamble Company (US) 2007-10-31 EP disclosed
WO-2006099341-A1 ABSORBENT ARTICLE HAVING BARRIER SHEET AGAINST THE TRANSFER OF THE SKIN CARE COMPOSITION THE PROCTER & GAMBLE COMPANY (US) 2006-09-21 WO disclosed
WO-2006088667-A1 SANITARY NAPKINS CAPABLE OF TAKING COMPLEX THREE-DIMENSIONAL SHAPE IN USE THE PROCTER & GAMBLE COMPANY (US) 2006-08-24 WO disclosed
EP-1432457-A1 SANITARY NAPKINS WITH HYDROPHOBIC LOTIONS THE PROCTER & GAMBLE COMPANY (US) 2004-06-30 EP disclosed
WO-2003028776-A1 SANITARY NAPKINS WITH HYDROPHOBIC LOTIONS THE PROCTER & GAMBLE COMPANY (US) 2003-04-10 WO disclosed