Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 8/20 | 0.64 |
| ▸ | MAPT | P10636 | 5/20 | 0.64 |
| ▸ | NPSR1 | Q6W5P4 | 4/20 | 0.64 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.64 |
| ▸ | HPGD | P15428 | 3/20 | 0.64 |
| ▸ | HTT | P42858 | 1/20 | 0.59 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.57 |
| ▸ | LMNA | P02545 | 2/20 | 0.57 |
| ▸ | USP2 | O75604 | 1/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.51 |
| ▸ | MEN1 | O00255 | 1/20 | 0.51 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.50 |
| ▸ | POLB | P06746 | 1/20 | 0.48 |
| ▸ | GAA | P10253 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL528228 | 0.91 | ALDH1A1 (0.80) | ALDH1A1MAPTNPSR1KDM4EHPGD | |
| SCHEMBL528469 | 0.90 | ALDH1A1 (0.57) | ALDH1A1MAPTNPSR1KDM4EHPGD | |
| SCHEMBL528449 | 0.90 | ALDH1A1 (0.67) | ALDH1A1MAPTNPSR1KDM4EHPGD | |
| SCHEMBL529111 | 0.87 | MAPT (0.64) | ALDH1A1MAPTNPSR1KDM4EHPGD | |
| SCHEMBL528208 | 0.87 | ALDH1A1 (0.64) | ALDH1A1MAPTNPSR1KDM4EHPGD | |
| SCHEMBL529488 | 0.86 | ALDH1A1 (0.63) | ALDH1A1MAPTNPSR1KDM4EHPGD | |
| SCHEMBL527892 | 0.85 | MAPT (0.73) | ALDH1A1MAPTNPSR1KDM4EHPGD | |
| SCHEMBL528988 | 0.85 | ALDH1A1 (0.62) | ALDH1A1MAPTNPSR1KDM4EHPGD | |
| SCHEMBL529121 | 0.84 | ALDH1A1 (0.64) | ALDH1A1MAPTNPSR1KDM4EHPGD | |
| SCHEMBL528058 | 0.84 | MEN1 (0.67) | ALDH1A1MAPTNPSR1KDM4EHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012014127-A1 | 5-LIPOXYGENASE INHIBITORS | RANBAXY LABORATORIES LIMITED (IN) | 2012-02-02 | — | — | WO | claimed |
| WO-2012014127-A1 | 5-LIPOXYGENASE INHIBITORS | RANBAXY LABORATORIES LIMITED (IN) | 2012-02-02 | — | — | WO | disclosed |