Cyclohexyl Fumarate

Cyclohexyl Fumarate

SCHEMBL528698

O=C(O)/C=C/C(=O)OC1CCCCC1

nearest known ligand 0.47

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ATM Q13315 1/20 0.47
HTT P42858 3/20 0.46
SMN1; SMN2 Q16637 2/20 0.46
NPC1 O15118 1/20 0.46
GAA P10253 1/20 0.46
EPHX1 P07099 2/20 0.42
HCAR2 Q8TDS4 3/20 0.41
CYP2C19 P33261 1/20 0.38
TSHR P16473 2/20 0.38
TP53 P04637 2/20 0.38
EGLN1 Q9GZT9 1/20 0.38
EGLN3 Q9H6Z9 1/20 0.38
CA12 O43570 1/20 0.38
CA1 P00915 1/20 0.38
CA2 P00918 1/20 0.38
CA9 Q16790 1/20 0.38
NAAA Q02083 1/20 0.37
MEN1 O00255 1/20 0.37
MITF O75030 1/20 0.37
LMNA P02545 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Maleic Acid SCHEMBL28065315 1.00 ATM (0.47) ATMHTTSMN1; SMN2NPC1GAA
Fumaric Acid SCHEMBL7564865 1.00 ATM (0.47) ATMHTTSMN1; SMN2NPC1GAA
SCHEMBL1087406 1.00 ATM (0.47) ATMHTTSMN1; SMN2NPC1GAA
Cyclohexyl Fumarate SCHEMBL528630 1.00 ATM (0.47) ATMHTTSMN1; SMN2NPC1GAA
SCHEMBL4158798 1.00 ATM (0.47) ATMHTTSMN1; SMN2NPC1GAA
SCHEMBL4156013 1.00 ATM (0.47) ATMHTTSMN1; SMN2NPC1GAA
SCHEMBL4156019 1.00 ATM (0.47) ATMHTTSMN1; SMN2NPC1GAA
Fumaric Acid SCHEMBL7564862 1.00 ATM (0.47) ATMHTTSMN1; SMN2NPC1GAA
Cyclohexyl Fumarate SCHEMBL528629 1.00 ATM (0.47) ATMHTTSMN1; SMN2NPC1GAA
SCHEMBL1087672 1.00 ATM (0.47) ATMHTTSMN1; SMN2NPC1GAA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1319 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3597677-B1 METHOD FOR PRODUCING A NITRILE GROUP-CONTAINING COPOLYMER RUBBER ZEON CORP (JP) 2022-10-19 EP claimed
CN-111995307-B Preparation method of protective coating material for marine peripheral buildings 湖北工业大学 2022-04-29 CN claimed
CN-114369197-A Polyalkylacrylate processing aid and melt-processable composition containing same 熵能创新材料(珠海)有限公司 2022-04-19 CN claimed
CN-110461892-B Nitrile group-containing copolymer rubber 日本瑞翁株式会社 2022-02-11 CN claimed
US-20200131293-A1 NITRILE GROUP-CONTAINING COPOLYMER RUBBER ZEON CORPORATION (JP) 2020-04-30 US claimed
EP-2145921-B1 Vulcanizable polymer compositions ARLANXEO DEUTSCHLAND GMBH (DE) 2017-01-25 EP claimed
US-8952099-B2 Vulcanizable polymer compositions LANXESS DEUTSCHLAND GMBH (DE) 2015-02-10 US claimed
EP-2199326-B1 Vulcanizable polymer compositions LANXESS DEUTSCHLAND GMBH (DE) 2014-10-29 EP claimed
US-8084542-B2 Shaped article composed of an acrylic rubber composition ZEON CORPORATION (JP) 2011-12-27 US claimed
US-20100179277-A1 VULCANIZABLE POLYMER COMPOSITIONS LANXESS DEUTSCHLAND GMBH (DE) 2010-07-15 US claimed
EP-2199326-A1 Vulcanizable polymer compositions Lanxess Deutschland GmbH (DE) 2010-06-23 EP claimed
US-20100029857-A1 VULCANIZABLE POLYMER COMPOSITIONS LANXESS DEUTSCHLAND GMBH (DE) 2010-02-04 US claimed
EP-2145921-A1 Vulcanizable polymer compositions Lanxess Deutschland GmbH (DE) 2010-01-20 EP claimed
EP-2145920-A1 Vulcanizable polymer compositions Lanxess Deutschland GmbH (DE) 2010-01-20 EP claimed
US-20090005512-A1 ACRYLIC RUBBER, CROSSLINKABLE ACRYLIC RUBBER COMPOSITION AND MOLDINGS MASUDA HIROFUMI 2009-01-01 US claimed
EP-1533326-B1 CROSSLINKABLE ACRYLIC RUBBER COMPOSITION AND MOLDINGS ZEON CORP (JP) 2008-01-09 EP claimed
JP-2269709-A None JP disclosed
JP-60192714-A None JP disclosed
EP-0055559-A2 Vinyl acetate interpolymer latices and electrographic recording material using same MONSANTO COMPANY (US) 1982-07-07 EP disclosed
US-4163789-A Anti-psychotic (cycloalkenylalkylpiperidino) benzamides ANPHAR, S.A. (ES) 1979-08-07 US disclosed