Cyclohexyl Fumarate

Cyclohexyl Fumarate

SCHEMBL528629

O=C(O)/C=C\C(=O)OC1CCCCC1

nearest known ligand 0.47

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ATM Q13315 1/20 0.47
HTT P42858 3/20 0.46
SMN1; SMN2 Q16637 2/20 0.46
NPC1 O15118 1/20 0.46
GAA P10253 1/20 0.46
EPHX1 P07099 2/20 0.42
HCAR2 Q8TDS4 3/20 0.41
CYP2C19 P33261 1/20 0.38
TSHR P16473 2/20 0.38
TP53 P04637 2/20 0.38
EGLN1 Q9GZT9 1/20 0.38
EGLN3 Q9H6Z9 1/20 0.38
CA12 O43570 1/20 0.38
CA1 P00915 1/20 0.38
CA2 P00918 1/20 0.38
CA9 Q16790 1/20 0.38
NAAA Q02083 1/20 0.37
MEN1 O00255 1/20 0.37
MITF O75030 1/20 0.37
LMNA P02545 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Maleic Acid SCHEMBL28065315 1.00 ATM (0.47) ATMHTTSMN1; SMN2NPC1GAA
Fumaric Acid SCHEMBL7564865 1.00 ATM (0.47) ATMHTTSMN1; SMN2NPC1GAA
Cyclohexyl Fumarate SCHEMBL528698 1.00 ATM (0.47) ATMHTTSMN1; SMN2NPC1GAA
SCHEMBL1087406 1.00 ATM (0.47) ATMHTTSMN1; SMN2NPC1GAA
Cyclohexyl Fumarate SCHEMBL528630 1.00 ATM (0.47) ATMHTTSMN1; SMN2NPC1GAA
SCHEMBL4158798 1.00 ATM (0.47) ATMHTTSMN1; SMN2NPC1GAA
SCHEMBL4156013 1.00 ATM (0.47) ATMHTTSMN1; SMN2NPC1GAA
SCHEMBL4156019 1.00 ATM (0.47) ATMHTTSMN1; SMN2NPC1GAA
Fumaric Acid SCHEMBL7564862 1.00 ATM (0.47) ATMHTTSMN1; SMN2NPC1GAA
SCHEMBL1087672 1.00 ATM (0.47) ATMHTTSMN1; SMN2NPC1GAA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1055 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-12139679-B2 Lubricity modifier for fuels and application thereof CHINA PETROLEUM & CHEMICAL CORPORATION (CN) 2024-11-12 US claimed
US-20230151290-A1 LUBRICITY MODIFIER FOR FUELS AND APPLICATION THEREOF CHINA PETROLEUM & CHEMICAL CORPORATION (CN) 2023-05-18 US claimed
EP-4130206-A1 FUEL LUBRICITY IMPROVER AND APPLICATION THEREOF China Petroleum & Chemical Corporation (CN) 2023-02-08 EP claimed
CN-111995307-B Preparation method of protective coating material for marine peripheral buildings 湖北工业大学 2022-04-29 CN claimed
CN-114369197-A Polyalkylacrylate processing aid and melt-processable composition containing same 熵能创新材料(珠海)有限公司 2022-04-19 CN claimed
CN-113462443-A Diesel antiwear agent composition, preparation method thereof and diesel composition 中国石油化工股份有限公司 2021-10-01 CN claimed
CN-111995307-A Preparation method of protective coating material for marine peripheral buildings 湖北工业大学 2020-11-27 CN claimed
EP-2666607-B1 TIRE BLADDER DENKA COMPANY LTD (JP) 2018-03-14 EP claimed
EP-2145921-B1 Vulcanizable polymer compositions ARLANXEO DEUTSCHLAND GMBH (DE) 2017-01-25 EP claimed
US-8952099-B2 Vulcanizable polymer compositions LANXESS DEUTSCHLAND GMBH (DE) 2015-02-10 US claimed
US-20100179277-A1 VULCANIZABLE POLYMER COMPOSITIONS LANXESS DEUTSCHLAND GMBH (DE) 2010-07-15 US claimed
EP-2199326-A1 Vulcanizable polymer compositions Lanxess Deutschland GmbH (DE) 2010-06-23 EP claimed
US-20100029857-A1 VULCANIZABLE POLYMER COMPOSITIONS LANXESS DEUTSCHLAND GMBH (DE) 2010-02-04 US claimed
EP-2145920-A1 Vulcanizable polymer compositions Lanxess Deutschland GmbH (DE) 2010-01-20 EP claimed
EP-2145921-A1 Vulcanizable polymer compositions Lanxess Deutschland GmbH (DE) 2010-01-20 EP claimed
US-20090005512-A1 ACRYLIC RUBBER, CROSSLINKABLE ACRYLIC RUBBER COMPOSITION AND MOLDINGS MASUDA HIROFUMI 2009-01-01 US claimed
EP-1533326-B1 CROSSLINKABLE ACRYLIC RUBBER COMPOSITION AND MOLDINGS ZEON CORP (JP) 2008-01-09 EP claimed
EP-0140530-B1 LATENTLY-CURABLE ORGANOSILICONE RELEASE COATING COMPOSITION MINNESOTA MINING AND MANUFACTURING COMPANY (US) 1989-03-08 EP claimed
EP-0140530-A1 Latently-curable organosilicone release coating composition MINNESOTA MINING AND MANUFACTURING COMPANY (US) 1985-05-08 EP claimed
US-4504645-A GELATION INHIBITION USING A MONOESTER OR -AMIDE OF AN UNSATURATED DICARBOXYLIC ACID; SHELF LIFE; HEAT CURING MINNESOTA MINING AND MANUFACTURING COMPANY (US) 1985-03-12 US claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12139679-B2 Lubricity modifier for fuels and application thereof F12, ACADM, ADH1A ATM 1551/4885HTT 4770/4885SMN1; SMN2 4253/4885
US-20230151290-A1 LUBRICITY MODIFIER FOR FUELS AND APPLICATION THEREOF F12, ACADM, ADH1A ATM 1551/4885HTT 4770/4885SMN1; SMN2 4253/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.