Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRM2 | Q14416 | 3/20 | 0.47 |
| ▸ | SLC9A1 | P19634 | 4/20 | 0.41 |
| ▸ | TOP2A | P11388 | 1/20 | 0.39 |
| ▸ | HCAR3 | P49019 | 2/20 | 0.34 |
| ▸ | GABRB3 | P28472 | 1/20 | 0.33 |
| ▸ | HTT | P42858 | 2/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | MAOB | P27338 | 1/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
| ▸ | CSNK2A2 | P19784 | 2/20 | 0.31 |
| ▸ | CSNK2B | P67870 | 2/20 | 0.31 |
| ▸ | CSNK2A1 | P68400 | 2/20 | 0.31 |
| ▸ | CSNK2A3 | Q8NEV1 | 2/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5280418 | 0.93 | SLC9A1 (0.44) | GRM2SLC9A1TOP2AHCAR3GABRB3 | |
| SCHEMBL5277061 | 0.93 | GRM2 (0.47) | GRM2SLC9A1TOP2AHCAR3HTT | |
| SCHEMBL5279790 | 0.89 | GRM2 (0.45) | GRM2SLC9A1TOP2AHCAR3GABRB3 | |
| SCHEMBL5273503 | 0.87 | GRM2 (0.45) | GRM2SLC9A1TOP2AHCAR3HTT | |
| SCHEMBL5273703 | 0.86 | SLC9A1 (0.44) | GRM2SLC9A1TOP2AHCAR3LMNA | |
| SCHEMBL5280655 | 0.85 | GRM2 (0.42) | GRM2SLC9A1TOP2AMAOB | |
| SCHEMBL5278727 | 0.82 | GRM2 (0.41) | GRM2SLC9A1TOP2AGABRB3KMT2A | |
| SCHEMBL5275375 | 0.81 | GRM2 (0.41) | GRM2SLC9A1TOP2AHCAR3CSNK2A2 | |
| SCHEMBL5282477 | 0.81 | GRM2 (0.41) | GRM2SLC9A1TOP2AHCAR3 | |
| SCHEMBL5280118 | 0.80 | SLC9A1 (0.45) | GRM2SLC9A1TOP2AHCAR3LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1859781-A2 | Brightening and/or colouring agent with triazoles | Henkel Kommanditgesellschaft auf Aktien (DE) | 2007-11-28 | — | — | EP | disclosed |