Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 5/20 | 0.62 |
| ▸ | DNMT1 | P26358 | 3/20 | 0.62 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.62 |
| ▸ | DNMT3B | Q9UBC3 | 1/20 | 0.62 |
| ▸ | PKM | P14618 | 1/20 | 0.62 |
| ▸ | MAPT | P10636 | 6/20 | 0.53 |
| ▸ | MEN1 | O00255 | 4/20 | 0.53 |
| ▸ | NPC1 | O15118 | 1/20 | 0.53 |
| ▸ | GAA | P10253 | 1/20 | 0.53 |
| ▸ | RAB9A | P51151 | 1/20 | 0.53 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.51 |
| ▸ | STAT3 | P40763 | 1/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.46 |
| ▸ | HTR2A | P28223 | 2/20 | 0.46 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.46 |
| ▸ | HTR1A | P08908 | 1/20 | 0.46 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.46 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.46 |
| ▸ | HTR1D | P28221 | 1/20 | 0.46 |
| ▸ | HTR1B | P28222 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5287512 | 1.00 | KMT2A (0.62) | KMT2ADNMT1CYP2C19DNMT3BPKM | |
| SCHEMBL14625611 | 0.80 | KMT2A (0.67) | KMT2ADNMT1CYP2C19DNMT3BPKM | |
| SCHEMBL1600730 | 0.78 | KMT2A (0.67) | KMT2ADNMT1CYP2C19DNMT3BPKM | |
| SCHEMBL1600733 | 0.78 | KMT2A (0.67) | KMT2ADNMT1CYP2C19DNMT3BPKM | |
| SCHEMBL11949518 | 0.77 | KMT2A (1.00) | KMT2ADNMT1CYP2C19DNMT3BPKM | |
| SCHEMBL164192 | 0.77 | KMT2A (1.00) | KMT2ADNMT1CYP2C19DNMT3BPKM | |
| SCHEMBL30167914 | 0.77 | KMT2A (1.00) | KMT2ADNMT1CYP2C19DNMT3BPKM | |
| SCHEMBL562060 | 0.77 | KMT2A (1.00) | KMT2ADNMT1CYP2C19DNMT3BPKM | |
| SCHEMBL5306820 | 0.76 | KMT2A (0.80) | KMT2ADNMT1CYP2C19DNMT3BPKM | |
| SCHEMBL5306824 | 0.76 | KMT2A (0.80) | KMT2ADNMT1CYP2C19DNMT3BPKM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007007054-A1 | PHTHALAMIDES, SUCCINIMIDES AND RELATED COMPOUNDS AND THEIR USE AS PHARMACEUTICALS | CANCER RESEARCH TECHNOLOGY LIMITED (GB) | 2007-01-18 | — | — | WO | disclosed |