SCHEMBL5287524

SCHEMBL5287524

CCN1C=CN(c2ccccc2)C1Cc1ccccc1

nearest known ligand 0.36

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CES2 O00748 4/20 0.36
CYP1A2 P05177 2/20 0.33
CYP2C19 P33261 2/20 0.33
LMNA P02545 1/20 0.33
CYP2C9 P11712 1/20 0.33
RECQL P46063 1/20 0.33
SMN1; SMN2 Q16637 1/20 0.33
NPSR1 Q6W5P4 1/20 0.33
TP53 P04637 1/20 0.33
GRM2 Q14416 1/20 0.33
SLC6A2 P23975 1/20 0.33
SLC6A4 P31645 1/20 0.33
SLC6A3 Q01959 1/20 0.33
CHRNA7 P36544 1/20 0.33
CARM1 Q86X55 1/20 0.32
PRMT6 Q96LA8 1/20 0.32
CYP3A4 P08684 1/20 0.32
GAA P10253 1/20 0.32
ELANE P08246 1/20 0.32
KCNH2 Q12809 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5290964 0.87 DRD2 (0.36) CES2CARM1PRMT6KCNH2
SCHEMBL3458318 0.86 TP53 (0.41) CES2TP53CARM1PRMT6KCNH2
SCHEMBL5282404 0.84 KCNH2 (0.40) SMN1; SMN2KCNH2
SCHEMBL3458031 0.84 CHRNA7 (0.35) CES2CHRNA7GAAELANE
SCHEMBL5288382 0.83 KCNH2 (0.45) KCNH2
SCHEMBL5292770 0.82 KCNH2 (0.47) KCNH2
SCHEMBL5291023 0.82 KCNH2 (0.47) KCNH2
SCHEMBL5302065 0.82 KCNH2 (0.47) KCNH2
SCHEMBL5816763 0.82 KCNH2 (0.47) KCNH2
SCHEMBL5307999 0.82 KCNH2 (0.47) KCNH2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2007006418-A1 IONIC-LIQUID-CONTAINING PRODUCTS FOR DYEING AND/OR BRIGHTENING KERATIN FIBRES HENKEL KOMMANDITGESELLSCHAFT AUF AKTIEN (DE) 2007-01-18 WO disclosed
WO-2006131234-A1 COSMETIC COMPOSITIONS COMPRISING IONIC LIQUIDS HENKEL KOMMANDITGESELLSCHAFT AUF AKTIEN (DE) 2006-12-14 WO disclosed