SCHEMBL5287554

SCHEMBL5287554

CCCCCCCCCCCCCCCCCCCN1C=CN(CCCCCCCCCCCCCCCCC)C1c1ccccc1

nearest known ligand 0.42

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 1/20 0.42
CYP1A2 P05177 1/20 0.42
CYP2D6 P10635 1/20 0.42
CYP2C19 P33261 1/20 0.42
KCNH2 Q12809 2/20 0.42
CNR2 P34972 3/20 0.41
CNR1 P21554 1/20 0.41
SLC9A1 P19634 2/20 0.38
CFTR P13569 1/20 0.38
NPC1 O15118 1/20 0.38
MITF O75030 1/20 0.38
GAA P10253 1/20 0.38
RAB9A P51151 1/20 0.38
L3MBTL1 Q9Y468 1/20 0.38
DRD2 P14416 4/20 0.38
HTR1A P08908 3/20 0.38
DRD1 P21728 3/20 0.38
DRD4 P21917 3/20 0.38
DRD5 P21918 3/20 0.38
DRD3 P35462 3/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5287355 1.00 ALDH1A1 (0.42) ALDH1A1CYP1A2CYP2D6CYP2C19KCNH2
SCHEMBL5810913 1.00 ALDH1A1 (0.42) ALDH1A1CYP1A2CYP2D6CYP2C19KCNH2
SCHEMBL5325451 1.00 ALDH1A1 (0.42) ALDH1A1CYP1A2CYP2D6CYP2C19KCNH2
SCHEMBL5815134 1.00 ALDH1A1 (0.42) ALDH1A1CYP1A2CYP2D6CYP2C19KCNH2
SCHEMBL5817075 1.00 ALDH1A1 (0.42) ALDH1A1CYP1A2CYP2D6CYP2C19KCNH2
SCHEMBL5286020 1.00 ALDH1A1 (0.42) ALDH1A1CYP1A2CYP2D6CYP2C19KCNH2
SCHEMBL5282940 1.00 ALDH1A1 (0.42) ALDH1A1CYP1A2CYP2D6CYP2C19KCNH2
SCHEMBL5303416 1.00 ALDH1A1 (0.42) ALDH1A1CYP1A2CYP2D6CYP2C19KCNH2
SCHEMBL5283135 1.00 ALDH1A1 (0.42) ALDH1A1CYP1A2CYP2D6CYP2C19KCNH2
SCHEMBL5292509 1.00 ALDH1A1 (0.42) ALDH1A1CYP1A2CYP2D6CYP2C19KCNH2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2007006418-A1 IONIC-LIQUID-CONTAINING PRODUCTS FOR DYEING AND/OR BRIGHTENING KERATIN FIBRES HENKEL KOMMANDITGESELLSCHAFT AUF AKTIEN (DE) 2007-01-18 WO disclosed
WO-2006131234-A1 COSMETIC COMPOSITIONS COMPRISING IONIC LIQUIDS HENKEL KOMMANDITGESELLSCHAFT AUF AKTIEN (DE) 2006-12-14 WO disclosed