Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.60 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.60 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.60 |
| ▸ | HRH3 | Q9Y5N1 | 2/20 | 0.58 |
| ▸ | MAOB | P27338 | 1/20 | 0.58 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL491572 | 1.00 | KDM4E (0.60) | KDM4EKMT2ATDP1HRH3MAOB | |
| SCHEMBL491506 | 1.00 | KDM4E (0.60) | KDM4EKMT2ATDP1HRH3MAOB | |
| SCHEMBL491505 | 1.00 | KDM4E (0.60) | KDM4EKMT2ATDP1HRH3MAOB | |
| SCHEMBL5284021 | 0.89 | LTA4H (0.54) | KDM4EKMT2ATDP1HRH3MAOB | |
| SCHEMBL4094374 | 0.88 | HRH3 (0.62) | KDM4EKMT2ATDP1HRH3MAOB | |
| SCHEMBL4094371 | 0.88 | HRH3 (0.62) | KDM4EKMT2ATDP1HRH3MAOB | |
| SCHEMBL4094378 | 0.88 | HRH3 (0.62) | KDM4EKMT2ATDP1HRH3MAOB | |
| SCHEMBL5295577 | 0.86 | KDM4E (0.56) | KDM4EKMT2ATDP1HRH3 | |
| SCHEMBL491666 | 0.85 | HRH3 (0.72) | KDM4EKMT2ATDP1HRH3MAOB | |
| SCHEMBL491668 | 0.85 | HRH3 (0.72) | KDM4EKMT2ATDP1HRH3MAOB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1863486-A2 | TREATMENT OF EPILEPSY WITH NON-IMIDAZOLE ALKYLAMINES HISTAMINE H3-RECEPTOR LIGANDS | BIOPROJET (FR) | 2007-12-12 | — | — | EP | disclosed |
| WO-2006103537-A2 | TREATMENT OF EPILEPSY WITH NON-IMIDAZOLE ALKYLAMINES HISTAMINE H3-RECEPTOR LIGANDS | BIOPROJET (FR) | 2006-10-05 | — | — | WO | disclosed |