SCHEMBL5287611

SCHEMBL5287611

CC/C=C\CN1CCCC1

nearest known ligand 0.43

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
CARM1 Q86X55 1/20 0.37
PRMT6 Q96LA8 1/20 0.37
PRMT8 Q9NR22 1/20 0.37
LTA4H P09960 1/20 0.36
LMNA P02545 1/20 0.32
CHRNB2 P17787 1/20 0.31
CHRNB4 P30926 1/20 0.31
CHRNA3 P32297 1/20 0.31
CHRNA4 P43681 1/20 0.31
HRH3 Q9Y5N1 1/20 0.31
CYP2D6 P10635 1/20 0.30
KMT2A Q03164 1/20 0.30
SIGMAR1 Q99720 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3305428 1.00 CARM1 (0.37) CARM1PRMT6PRMT8LTA4HLMNA
SCHEMBL11953077 1.00 CARM1 (0.37) CARM1PRMT6PRMT8LTA4HLMNA
SCHEMBL19073860 0.97 CARM1 (0.36) CARM1PRMT6PRMT8LTA4HLMNA
SCHEMBL3306863 0.97 CARM1 (0.36) CARM1PRMT6PRMT8LTA4HLMNA
SCHEMBL16853209 0.89 KDM4E (0.32)
SCHEMBL23872300 0.86 LTA4H (0.42) CARM1PRMT6PRMT8LTA4HLMNA
SCHEMBL23872301 0.83 HRH3 (0.43) CARM1PRMT6PRMT8LTA4HLMNA
SCHEMBL10748748 0.83 HRH3 (0.43) CARM1PRMT6PRMT8LTA4HLMNA
SCHEMBL7227482 0.83 HRH3 (0.43) CARM1PRMT6PRMT8LTA4HLMNA
SCHEMBL14274107 0.82 CHRNA7 (0.34) HRH3KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2023196527-A2 IONIZABLE LIPID COMPOUNDS AND LIPID NANOPARTICLE COMPOSITIONS SunVax mRNA Therapeutics Inc. (US) 2023-10-12 WO disclosed
EP-1863780-A1 PREPARATION OF OPTICALLY PURE BETA-AMINO ACIDS HAVING AFFINITY FOR THE ALPHA-2-DELTA PROTEIN Pharmacia & Upjohn Company LLC (US) 2007-12-12 EP disclosed
WO-2006100568-A1 PREPARATION OF OPTICALLY PURE BETA-AMINO ACIDS HAVING AFFINITY FOR THE ALPHA-2-DELTA PROTEIN PHARMACIA & UPJOHN COMPANY LLC (US) 2006-09-28 WO disclosed