Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADAM17 | P78536 | 17/20 | 0.81 |
| ▸ | MMP2 | P08253 | 3/20 | 0.81 |
| ▸ | MMP9 | P14780 | 3/20 | 0.53 |
| ▸ | MMP3 | P08254 | 1/20 | 0.53 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | NPC1 | O15118 | 1/20 | 0.44 |
| ▸ | RAB9A | P51151 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
| ▸ | MAOB | P27338 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5295607 | 0.91 | ADAM17 (0.74) | ADAM17MMP2MMP9MMP3MAOB | |
| SCHEMBL5289796 | 0.90 | ADAM17 (1.00) | ADAM17MMP2MMP9MAOB | |
| SCHEMBL5291136 | 0.86 | ADAM17 (0.63) | ADAM17MMP2MMP9MMP3MEN1 | |
| SCHEMBL5302828 | 0.86 | ADAM17 (0.65) | ADAM17MMP2MMP9MMP3MAOB | |
| SCHEMBL5285025 | 0.86 | ADAM17 (0.65) | ADAM17MMP2MMP9MMP3MEN1 | |
| Hydrochloric Acid SCHEMBL5291124 | 0.85 | ADAM17 (0.62) | ADAM17MMP2MMP9MMP3MEN1 | |
| SCHEMBL5294818 | 0.84 | ADAM17 (0.73) | ADAM17MMP2MMP9MEN1NPC1 | |
| SCHEMBL5293765 | 0.84 | ADAM17 (0.83) | ADAM17MMP2MMP9MEN1NPC1 | |
| SCHEMBL5289147 | 0.83 | ADAM17 (0.84) | ADAM17MMP2MMP9MMP3MEN1 | |
| SCHEMBL5285553 | 0.80 | ADAM17 (0.67) | ADAM17MMP2MMP9MMP3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007008037-A1 | NOVEL CHROMEN-2-ONE BASED HYDROXAMIC ACID DERIVATIVES HAVING ANTI-INFLAMMATORY ACTIVITY, THE PREPARATION THEREOF AND A COMPOSITION CONTAINING THE SAME FOR TREATING INFLAMMATORY DISEASE | JEIL PHARMACEUTICAL CO., LTD. (KR) | 2007-01-18 | — | — | WO | disclosed |