Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 4/20 | 0.65 |
| ▸ | XBP1 | P17861 | 1/20 | 0.65 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.65 |
| ▸ | KMT2A | Q03164 | 7/20 | 0.61 |
| ▸ | MEN1 | O00255 | 6/20 | 0.61 |
| ▸ | NPC1 | O15118 | 3/20 | 0.61 |
| ▸ | POLB | P06746 | 2/20 | 0.61 |
| ▸ | RAB9A | P51151 | 2/20 | 0.61 |
| ▸ | MITF | O75030 | 1/20 | 0.61 |
| ▸ | NCOA3 | Q9Y6Q9 | 2/20 | 0.60 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.60 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.58 |
| ▸ | DDX3X | O00571 | 1/20 | 0.56 |
| ▸ | CTDSP1 | Q9GZU7 | 1/20 | 0.56 |
| ▸ | NCOA1 | Q15788 | 1/20 | 0.55 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5287845 | 1.00 | MAPT (0.65) | MAPTXBP1MAPK1KMT2AMEN1 | |
| SCHEMBL14625231 | 0.88 | MAPT (0.60) | MAPTXBP1MAPK1KMT2AMEN1 | |
| SCHEMBL12008920 | 0.81 | FFAR1 (0.64) | MAPTMAPK1KMT2AMEN1NPC1 | |
| SCHEMBL12008788 | 0.80 | MAPT (0.87) | MAPTXBP1MAPK1KMT2AMEN1 | |
| SCHEMBL12008760 | 0.77 | KMT2A (0.90) | MAPTXBP1MAPK1KMT2AMEN1 | |
| SCHEMBL12008758 | 0.76 | MAPT (1.00) | MAPTKMT2AMEN1NPC1POLB | |
| SCHEMBL12008419 | 0.76 | KMT2A (1.00) | MAPTXBP1MAPK1KMT2AMEN1 | |
| SCHEMBL5992046 | 0.76 | MEN1 (1.00) | MAPTXBP1MAPK1KMT2AMEN1 | |
| SCHEMBL12008879 | 0.76 | KMT2A (0.62) | MAPTKMT2AMEN1NPC1POLB | |
| SCHEMBL19736098 | 0.75 | MAPT (0.81) | MAPTXBP1MAPK1KMT2AMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007002587-A2 | INHIBITORS OF EPSTEIN BARR VIRUS NUCLEAR ANTIGEN 1 | THE BRIGHAM AND WOMEN'S HOSPITAL, INC. (US) | 2007-01-04 | — | — | WO | claimed |