Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 16/20 | 1.00 |
| ▸ | KMT2A | Q03164 | 16/20 | 1.00 |
| ▸ | MAPT | P10636 | 5/20 | 1.00 |
| ▸ | RAB9A | P51151 | 3/20 | 1.00 |
| ▸ | NPC1 | O15118 | 3/20 | 1.00 |
| ▸ | MITF | O75030 | 2/20 | 1.00 |
| ▸ | PSMD14 | O00487 | 1/20 | 0.82 |
| ▸ | POLB | P06746 | 4/20 | 0.73 |
| ▸ | MAPK1 | P28482 | 4/20 | 0.70 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.70 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.70 |
| ▸ | LMNA | P02545 | 2/20 | 0.70 |
| ▸ | XBP1 | P17861 | 1/20 | 0.70 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.69 |
| ▸ | ALPL | P05186 | 2/20 | 0.69 |
| ▸ | HPGD | P15428 | 1/20 | 0.69 |
| ▸ | RECQL | P46063 | 1/20 | 0.69 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.67 |
| ▸ | SAE1 | Q9UBE0 | 1/20 | 0.67 |
| ▸ | UBA2 | Q9UBT2 | 1/20 | 0.67 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12008419 | 0.84 | KMT2A (1.00) | MEN1KMT2AMAPTRAB9ANPC1 | |
| SCHEMBL12008788 | 0.80 | MAPT (0.87) | MEN1KMT2AMAPTRAB9ANPC1 | |
| SCHEMBL13345901 | 0.79 | KMT2A (0.85) | MEN1KMT2AMAPTRAB9ANPC1 | |
| SCHEMBL11918202 | 0.79 | KMT2A (1.00) | MEN1KMT2AMAPTRAB9ANPC1 | |
| SCHEMBL13888265 | 0.77 | KMT2A (0.85) | MEN1KMT2AMAPTRAB9ANPC1 | |
| SCHEMBL12008760 | 0.77 | KMT2A (0.90) | MEN1KMT2AMAPTRAB9ANPC1 | |
| SCHEMBL12008757 | 0.76 | KMT2A (0.90) | MEN1KMT2AMAPTRAB9ANPC1 | |
| SCHEMBL12008578 | 0.76 | KMT2A (0.84) | MEN1KMT2AMAPTRAB9APOLB | |
| SCHEMBL12008758 | 0.76 | MAPT (1.00) | MEN1KMT2AMAPTRAB9ANPC1 | |
| SCHEMBL5287842 | 0.76 | MAPT (0.65) | MEN1KMT2AMAPTRAB9ANPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012065139-A2 | ENTPD5 INHIBITORS | BOARD OF REGENTS, THE UNIVERSITY OF TEXAS SYSTEM (US) | 2012-05-18 | — | — | WO | disclosed |