SCHEMBL5287967

SCHEMBL5287967

CC(C)c1ccc(OC(=O)c2cc(Cl)cc(Cl)c2)cc1

nearest known ligand 0.55

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
PRSS1 P07477 1/20 0.55
ACR P10323 1/20 0.55
THRB P10828 1/20 0.52
HPGD P15428 1/20 0.50
XBP1 P17861 1/20 0.50
MAPT P10636 3/20 0.48
KMT2A Q03164 2/20 0.47
PABPC1 P11940 1/20 0.47
EIF4H Q15056 1/20 0.47
CTDSP1 Q9GZU7 1/20 0.47
LMNA P02545 2/20 0.47
CNR1 P21554 1/20 0.47
CNR2 P34972 1/20 0.47
SMN1; SMN2 Q16637 2/20 0.45
MEN1 O00255 1/20 0.44
HTT P42858 1/20 0.43
ALDH1A1 P00352 2/20 0.43
CTRC Q99895 1/20 0.43
KDM4E B2RXH2 1/20 0.43
RXRA P19793 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL19237516 0.85 PRSS1 (0.64) PRSS1ACRTHRBHPGDXBP1
SCHEMBL29004327 0.84 PRSS1 (0.71) PRSS1ACRTHRBHPGDXBP1
SCHEMBL8387961 0.83 CYP1A2 (0.57) PRSS1ACRHPGDMAPTKMT2A
SCHEMBL4732803 0.82 NSD2 (0.63) PRSS1ACRTHRBHPGDXBP1
SCHEMBL5292727 0.82 HPGD (0.56) PRSS1ACRTHRBHPGDXBP1
SCHEMBL8210768 0.79 PRSS1 (0.61) PRSS1ACRHPGDXBP1MAPT
SCHEMBL29004335 0.78 PRSS1 (0.64) PRSS1ACRHPGDXBP1MAPT
SCHEMBL9618044 0.76 PRSS1 (0.55) PRSS1ACRTHRBHPGDXBP1
SCHEMBL9906007 0.76 PRSS1 (0.58) PRSS1ACRHPGDXBP1MAPT
SCHEMBL19237514 0.76 NR1H4 (0.58) THRBHPGDXBP1MAPTKMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2007004753-A1 ALKYLPHENOL DERIVATIVES HAVING PHYTOPATHOGENIC FUNGI ACTIVITIES DONGBU HITEK CO., LTD. (KR) 2007-01-11 WO claimed
WO-2007004753-A1 ALKYLPHENOL DERIVATIVES HAVING PHYTOPATHOGENIC FUNGI ACTIVITIES DONGBU HITEK CO., LTD. (KR) 2007-01-11 WO disclosed