SCHEMBL9906007

SCHEMBL9906007

CCC(O)c1ccc(C(=O)Oc2ccc(C(C)C)cc2)cc1

nearest known ligand 0.58

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
PRSS1 P07477 2/20 0.58
ACR P10323 2/20 0.58
HPGD P15428 1/20 0.47
XBP1 P17861 1/20 0.47
ESR1 P03372 1/20 0.46
HIF1A Q16665 1/20 0.46
SMN1; SMN2 Q16637 3/20 0.46
MAPT P10636 4/20 0.45
RXRA P19793 1/20 0.44
RXRB P28702 1/20 0.44
KMT2A Q03164 3/20 0.43
ALDH1A1 P00352 3/20 0.42
PABPC1 P11940 1/20 0.42
EIF4H Q15056 1/20 0.42
CTDSP1 Q9GZU7 1/20 0.42
NPC1 O15118 1/20 0.42
RAB9A P51151 1/20 0.42
MEN1 O00255 1/20 0.41
LMNA P02545 1/20 0.41
HSD17B10 Q99714 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10197130 0.88 MAPT (0.49) PRSS1ACRESR1HIF1AMAPT
SCHEMBL9906003 0.88 LMNA (0.54) PRSS1ACRESR1HIF1ASMN1; SMN2
SCHEMBL29004327 0.87 PRSS1 (0.71) PRSS1ACRHPGDXBP1SMN1; SMN2
SCHEMBL10074562 0.87 KMT2A (0.58) PRSS1ACRHPGDESR1HIF1A
SCHEMBL19237516 0.81 PRSS1 (0.64) PRSS1ACRHPGDXBP1SMN1; SMN2
SCHEMBL29004335 0.81 PRSS1 (0.64) PRSS1ACRHPGDXBP1SMN1; SMN2
SCHEMBL9905989 0.81 PRSS1 (0.57) PRSS1ACRSMN1; SMN2MAPTRXRA
SCHEMBL9906005 0.80 ESR1 (0.40) PRSS1ACRESR1HIF1AMAPT
SCHEMBL8210768 0.79 PRSS1 (0.61) PRSS1ACRHPGDXBP1MAPT
SCHEMBL8422497 0.79 PRSS1 (0.61) PRSS1ACRHPGDXBP1SMN1; SMN2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8197726-B2 Cellulose acylate film and method for producing same FUJIFILM CORPORATION (JP) 2012-06-12 US disclosed
US-20080111954-A1 Cellulose Acylate Film And Method For Producing Same FUJIFILM CORPORATION (JP) 2008-05-15 US disclosed