SCHEMBL5288147

SCHEMBL5288147

CSc1ccc(OCCOc2ccccc2)cc1

nearest known ligand 0.54

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KCNA3 P22001 1/20 0.54
LTA4H P09960 5/20 0.52
PKM P14618 2/20 0.50
CHRNB2 P17787 2/20 0.50
CHRNB4 P30926 2/20 0.50
CHRNA3 P32297 2/20 0.50
CHRNA7 P36544 2/20 0.50
CHRNA4 P43681 2/20 0.50
MAPT P10636 1/20 0.49
RAB9A P51151 1/20 0.49
HTR1B P28222 2/20 0.48
HTR1D P28221 1/20 0.48
ALDH1A1 P00352 2/20 0.48
TAAR1 Q96RJ0 1/20 0.48
RECQL P46063 1/20 0.48
PARP10 Q53GL7 1/20 0.47
PLA2G2A P14555 1/20 0.47
HPGD P15428 1/20 0.47
GAA P10253 1/20 0.46
SMN1; SMN2 Q16637 1/20 0.46

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5287407 0.94 KCNA3 (0.64) KCNA3LTA4HCHRNB2CHRNB4CHRNA3
SCHEMBL10441158 0.91 MAOB (0.49) MAPTALDH1A1GAA
SCHEMBL8672424 0.85 MAOB (0.45) MAPTALDH1A1RECQLSMN1; SMN2
SCHEMBL9808245 0.85 MAOB (0.47) KCNA3LTA4HMAPTALDH1A1GAA
SCHEMBL9808289 0.85 KCNA3 (0.48) KCNA3LTA4HMAPTALDH1A1GAA
SCHEMBL13181275 0.84 LTA4H (0.39) KCNA3LTA4HPKMCHRNB2CHRNB4
SCHEMBL24495061 0.83 CYP1A1 (0.46) MAPTRAB9AALDH1A1RECQLHPGD
SCHEMBL9665473 0.81 LTA4H (0.52) LTA4HMAPTRAB9AALDH1A1HPGD
SCHEMBL8361631 0.81 LTA4H (0.53) LTA4HRAB9AGAA
SCHEMBL7909500 0.80 LTA4H (0.57) LTA4HSMN1; SMN2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2006138653-A9 THERMAL RECORDING MATERIALS AND METHODS OF MAKING AND USING THE SAME NASHUA CORP (US) 2007-03-01 WO disclosed
US-20060293181-A1 Thermal recording materials and methods of making and using the same NASHUA CORPORATION 2006-12-28 US disclosed
WO-2006138653-A1 THERMAL RECORDING MATERIALS AND METHODS OF MAKING AND USING THE SAME NASHUA CORPORATION (US) 2006-12-28 WO disclosed
US-RE36321-E INCLUDING DIARYL DIETHER COMPOUND KANSAKI PAPER MANUFACTURING CO., LTD. (JP) 1999-09-28 US disclosed
EP-0141170-B1 HEAT-SENSITIVE RECORDING MATERIAL KANZAKI PAPER MANUFACTURING COMPANY LIMITED (JP) 1987-05-13 EP disclosed
US-4531140-A Heat-sensitive recording material Kansaki Paper Manufacturing Co. Ltd. (JP) 1985-07-23 US disclosed
EP-0141170-A2 Heat-sensitive recording material KANZAKI PAPER MANUFACTURING COMPANY LIMITED (JP) 1985-05-15 EP disclosed