SCHEMBL5289149

SCHEMBL5289149

CCCC[N+]1(Cc2ccccc2)CCCC1

nearest known ligand 0.44

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CYP2D6 P10635 1/20 0.40
NPC1 O15118 1/20 0.39
RAB9A P51151 1/20 0.39
KCNH2 Q12809 2/20 0.37
SMN1; SMN2 Q16637 2/20 0.36
SIGMAR1 Q99720 1/20 0.36
TP53 P04637 2/20 0.35
HTT P42858 2/20 0.35
APOBEC3A P31941 2/20 0.35
APOBEC3G Q9HC16 2/20 0.35
RGS12 O14924 1/20 0.35
CHRNA7 P36544 2/20 0.35
DNM1 Q05193 1/20 0.35
LMNA P02545 1/20 0.35
HIF1A Q16665 1/20 0.34
CHRM2 P08172 1/20 0.34
HTR1A P08908 1/20 0.34
ADRA2A P08913 1/20 0.34
CHRM1 P11229 1/20 0.34
DRD1 P21728 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5944606 0.98 NPC1 (0.41) CYP2D6NPC1RAB9AKCNH2SMN1; SMN2
SCHEMBL8965305 0.98 NPC1 (0.41) CYP2D6NPC1RAB9AKCNH2SMN1; SMN2
SCHEMBL5290866 0.95 CYP2D6 (0.39) CYP2D6NPC1RAB9AKCNH2SMN1; SMN2
SCHEMBL5306609 0.93 DNM1 (0.40) CYP2D6NPC1RAB9AKCNH2SMN1; SMN2
SCHEMBL5289768 0.93 DNM1 (0.40) CYP2D6NPC1RAB9AKCNH2SMN1; SMN2
SCHEMBL5301390 0.93 DNM1 (0.40) CYP2D6NPC1RAB9AKCNH2SMN1; SMN2
SCHEMBL5290733 0.93 DNM1 (0.40) CYP2D6NPC1RAB9AKCNH2SMN1; SMN2
SCHEMBL5284891 0.93 DNM1 (0.40) CYP2D6NPC1RAB9AKCNH2SMN1; SMN2
SCHEMBL5817360 0.93 DNM1 (0.40) CYP2D6NPC1RAB9AKCNH2SMN1; SMN2
SCHEMBL5286554 0.93 DNM1 (0.40) CYP2D6NPC1RAB9AKCNH2SMN1; SMN2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2007006418-A1 IONIC-LIQUID-CONTAINING PRODUCTS FOR DYEING AND/OR BRIGHTENING KERATIN FIBRES HENKEL KOMMANDITGESELLSCHAFT AUF AKTIEN (DE) 2007-01-18 WO disclosed
WO-2006131234-A1 COSMETIC COMPOSITIONS COMPRISING IONIC LIQUIDS HENKEL KOMMANDITGESELLSCHAFT AUF AKTIEN (DE) 2006-12-14 WO disclosed
US-20060186419-A1 Light-emitting device KABUSHIKI KAISHA TOSHIBA (JP) 2006-08-24 US disclosed
EP-0758643-B1 Process for the preparation of ortho-nitro-benzonitriles CLARIANT GMBH (DE) 2000-05-17 EP disclosed
US-5705674-A Process for preparing ortho-nitrobenzonitriles HOECHST AKTIENGESELLSCHAFT (DE) 1998-01-06 US disclosed
EP-0758643-A2 Process for the preparation of ortho-nitro-benzonitriles HOECHST AKTIENGESELLSCHAFT (DE) 1997-02-19 EP disclosed
EP-0619300-B1 Process for the preparation of halogenmethylbenzoyl cyanides and halogenmethyl benzoylcyanides BASF AG (DE) 1996-12-27 EP disclosed
US-5510528-A Preparation of halomethylbenzoly cyanides and novel halomethylbenzoyl cyanides BASF AKTIENGESELLSCHAFT (DE) 1996-04-23 US disclosed
US-5446199-A Preparation of halomethylbenzoyl cyanides and novel halomethylbenzoyl cyanides BASF AKTIENGESELLSCHAFT (DE) 1995-08-29 US disclosed
EP-0619300-A2 Process for the preparation of halogenmethylbenzoyl cyanides and halogenmethyl benzoylcyanides BASF Aktiengesellschaft (DE) 1994-10-12 EP disclosed