Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE4B | Q07343 | 1/20 | 0.40 |
| ▸ | USP30 | Q70CQ3 | 5/20 | 0.38 |
| ▸ | USP2 | O75604 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | GPR119 | Q8TDV5 | 4/20 | 0.37 |
| ▸ | MAPT | P10636 | 2/20 | 0.35 |
| ▸ | NPC1 | O15118 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.35 |
| ▸ | HTT | P42858 | 1/20 | 0.35 |
| ▸ | RAB9A | P51151 | 1/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.35 |
| ▸ | EPHA2 | P29317 | 2/20 | 0.35 |
| ▸ | RECQL | P46063 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | THRB | P10828 | 1/20 | 0.35 |
| ▸ | PRMT5 | O14744 | 1/20 | 0.35 |
| ▸ | WDR77 | Q9BQA1 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5289397 | 1.00 | PDE4B (0.40) | PDE4BUSP30USP2SMN1; SMN2GPR119 | |
| SCHEMBL5289408 | 1.00 | PDE4B (0.40) | PDE4BUSP30USP2SMN1; SMN2GPR119 | |
| SCHEMBL3329066 | 0.88 | GPR119 (0.44) | PDE4BUSP30USP2SMN1; SMN2GPR119 | |
| SCHEMBL13299453 | 0.88 | GPR119 (0.44) | PDE4BUSP30USP2SMN1; SMN2GPR119 | |
| SCHEMBL3325332 | 0.88 | GPR119 (0.44) | PDE4BUSP30USP2SMN1; SMN2GPR119 | |
| SCHEMBL3327776 | 0.88 | GPR119 (0.44) | PDE4BUSP30USP2SMN1; SMN2GPR119 | |
| SCHEMBL970288 | 0.88 | STS (0.44) | PDE4BUSP30SMN1; SMN2MAPTEPHA2 | |
| SCHEMBL970289 | 0.88 | STS (0.44) | PDE4BUSP30SMN1; SMN2MAPTEPHA2 | |
| SCHEMBL970287 | 0.88 | STS (0.44) | PDE4BUSP30SMN1; SMN2MAPTEPHA2 | |
| SCHEMBL3329274 | 0.87 | USP30 (0.45) | USP30USP2SMN1; SMN2GPR119KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007005935-A2 | NOREPINEPHRINE TRANSPORTER RADIOTRACERS AND METHODS OF SYNTHESES THEREOF | MOLECULAR NEUROIMAGING, LLC (US) | 2007-01-11 | — | — | WO | disclosed |