SCHEMBL5290

SCHEMBL5290

[CH2]C(F)(F)F

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL712072 0.83
SCHEMBL17456627 0.77
SCHEMBL15091211 0.72
SCHEMBL20803 0.72
SCHEMBL146024 0.72
SCHEMBL15226230 0.72
SCHEMBL18931 0.72
SCHEMBL10565743 0.72
SCHEMBL21875144 0.72
SCHEMBL25401 0.72

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Appears in 126676 patents — a generic fragment claimed broadly, so it's down-weighted as IP noise. Top by claim status then date:

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6362369-B1 None US claimed
US-12042495-B2 MAP4K1 inhibitors BLUEPRINT MEDICINES CORPORATION (US) 2024-07-23 US claimed
CN-118356775-A Novel fluorine functionalized alcohol amine-based absorbent for capturing sulfur dioxide in mixed gas, preparation method and application 大连理工大学 2024-07-19 CN claimed
WO-2024149189-A1 AROMATIC AMIDE DERIVATIVE, PREPARATION METHOD THEREFOR, AND USE THEREOF 浙江海正药业股份有限公司 2024-07-18 WO claimed
US-20240238445-A1 INHIBITORS AND USES THEREOF NEURACLE SCIENCE CO., LTD. (KR) 2024-07-18 US claimed
WO-2024149819-A1 SULFONYLVINYL COMPOUNDS FOR THE TREATMENT OF CANCER F. HOFFMANN-LA ROCHE AG (CH) 2024-07-18 WO claimed
US-20240238265-A1 ADAMANTANE AMIDES AND THIOAMIDES FOR THE TREATMENT OF EBOLAVIRUS INFECTION ARISAN THERAPEUTICS INC. (US) 2024-07-18 US claimed
US-20240239759-A1 ISOXAZOLINE COMPOSITIONS AND THEIR USE AS ANTIPARASITICS INTERVET INC. (US) 2024-07-18 US claimed
EP-4121802-B1 HIGH REFRACTIVE INDEX SILOXANE INSERT MATERIALS FOR EMBEDDED CONTACT LENSES ALCON INC (CH) 2024-07-17 EP claimed
CN-118344315-A Preparation and application of trifluoro thioether (sulfoxide) aromatic amine derivative 顺毅股份有限公司 2024-07-16 CN claimed
US-3995641-A Surgical adhesives ETHICON, INC. (US) 1976-12-07 US claimed
US-3989749-A RENAL VASODILATORS, ANTITHROMBUS MERCK & CO., INC. (US) 1976-11-02 US claimed
US-3987091-A RENAL VASODILATORS MERCK & CO., INC. (US) 1976-10-19 US claimed
US-3985726-A DYEING AND PRINTING LEATHER, WOOL, SILK AND SYNTHETIC FIBERS CIBA-GEIGY AG (CH) 1976-10-12 US claimed
US-3984415-A ANTIINFLAMMATORY, ANTI-ULCERATIVE, ANALGETIC, ANTIPYRETIC, ANTIHISTAMINIC AND CNS DEPRESSANTS HISAMITSU PHARMACEUTICAL CO., INC. (JA) 1976-10-05 US claimed
US-3971740-A DYES FOR POLYESTER FIBERS CIBA-GEIGY AG (CH) 1976-07-27 US claimed
US-3964907-A Method for the preparation of relief printing masters XEROX CORPORATION (US) 1976-06-22 US claimed
US-3956307-A FUNGICIDES SCHERING AKTIENGESELLSCHAFT (DT) 1976-05-11 US claimed
US-3947408-A ANTIANXIETY AGENTS AMERICAN CYANAMID COMPANY (US) 1976-03-30 US claimed
US-3941829-A PESTICIDE CIBA-GEIGY CORPORATION (US) 1976-03-02 US claimed