Biphenyl

Biphenyl

SCHEMBL5290676

C[SiH2]O[SiH3].c1ccc(-c2ccccc2)cc1

nearest known ligand 0.50

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 2/20 0.50
SLC22A2 O15244 1/20 0.40
SLC22A1 O15245 1/20 0.40
SLC22A3 O75751 1/20 0.40
SLC6A4 P31645 1/20 0.40
CYP1A2 P05177 3/20 0.38
TAAR1 Q96RJ0 3/20 0.38
MAPK1 P28482 1/20 0.38
CYP3A4 P08684 1/20 0.38
HSD17B10 Q99714 1/20 0.38
TDP1 Q9NUW8 1/20 0.38
NOTUM Q6P988 1/20 0.38
MMP3 P08254 1/20 0.38
BCL2L1 Q07817 1/20 0.38
SMN1; SMN2 Q16637 2/20 0.36
CYP1A1 P04798 1/20 0.36
CYP1B1 Q16678 1/20 0.36
AKT1 P31749 1/20 0.36
AKT2 P31751 1/20 0.36
MAPT P10636 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Biphenyl SCHEMBL5194632 0.84 ALDH1A1 (0.39) ALDH1A1SLC22A2SLC22A1SLC22A3SLC6A4
Biphenyl SCHEMBL15542338 0.80 ALDH1A1 (0.53) ALDH1A1SLC22A2SLC22A1SLC22A3SLC6A4
Biphenyl SCHEMBL7639292 0.79 ALDH1A1 (0.60) ALDH1A1SLC22A2SLC22A1SLC22A3SLC6A4
Biphenyl SCHEMBL9483986 0.78 ALDH1A1 (0.69) ALDH1A1SLC22A2SLC22A1SLC22A3SLC6A4
Biphenyl SCHEMBL27348895 0.78 ALDH1A1 (0.69) ALDH1A1SLC22A2SLC22A1SLC22A3SLC6A4
Biphenyl SCHEMBL6116263 0.78 ALDH1A1 (0.69) ALDH1A1SLC22A2SLC22A1SLC22A3SLC6A4
Biphenyl SCHEMBL27732120 0.76 ALDH1A1 (0.47) ALDH1A1SLC22A2SLC22A1SLC22A3SLC6A4
SCHEMBL11564136 0.75
Biphenyl SCHEMBL3990404 0.75 ALDH1A1 (0.75) ALDH1A1SLC22A2SLC22A1SLC22A3SLC6A4
Biphenyl SCHEMBL4466468 0.73 ALDH1A1 (0.60) ALDH1A1SLC22A2SLC22A1SLC22A3SLC6A4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1861704-A2 IDENTIFICATION OF BACTERIA AND SPORES Correlogic Systems, Inc. (US) 2007-12-05 EP disclosed
WO-2007053170-A2 IDENTIFICATION OF BACTERIA AND SPORES CORRELOGIC SYSTEMS, INC. (US) 2007-05-10 WO disclosed
US-20070003996-A1 Identification of bacteria and spores VERMILLION, INC. 2007-01-04 US disclosed