Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 2/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.42 |
| ▸ | CXCR4 | P61073 | 2/20 | 0.39 |
| ▸ | SIGMAR1 | Q99720 | 3/20 | 0.37 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | LTA4H | P09960 | 1/20 | 0.35 |
| ▸ | HRH2 | P25021 | 1/20 | 0.34 |
| ▸ | HRH1 | P35367 | 1/20 | 0.34 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5293272 | 0.89 | SIGMAR1 (0.41) | MEN1KMT2AKDM4EALDH1A1TDP1 | |
| SCHEMBL272713 | 0.85 | CXCR4 (0.46) | MEN1KMT2AKDM4EALDH1A1CXCR4 | |
| SCHEMBL5544476 | 0.84 | CXCR4 (0.47) | MEN1KMT2AKDM4EALDH1A1CXCR4 | |
| SCHEMBL23987984 | 0.82 | CXCR4 (0.52) | MEN1KMT2AKDM4EALDH1A1TDP1 | |
| Hydrochloric Acid SCHEMBL27805378 | 0.82 | CXCR4 (0.46) | MEN1KMT2AKDM4EALDH1A1CXCR4 | |
| SCHEMBL25113525 | 0.82 | MEN1 (0.44) | MEN1KMT2AKDM4EALDH1A1TDP1 | |
| SCHEMBL18232500 | 0.78 | CXCR4 (0.41) | MEN1KMT2AKDM4EALDH1A1TDP1 | |
| SCHEMBL2448790 | 0.77 | MEN1 (0.44) | MEN1KMT2AKDM4EALDH1A1TDP1 | |
| SCHEMBL16758734 | 0.76 | MEN1 (0.49) | MEN1KMT2AKDM4EALDH1A1TDP1 | |
| SCHEMBL20745043 | 0.76 | MEN1 (0.49) | MEN1KMT2AKDM4EALDH1A1TDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007004234-A1 | A PROCESS FOR THE PREPARATION OF 2-[2-(4-DIBENZO[b,f] [L,4] THIAZEPIN-11-yl-1- PIPERAZINYL)ETHOXY] ETHANOL FUMARATE | USV LIMITED (IN) | 2007-01-11 | — | — | WO | disclosed |
| US-6492355-B1 | Adamantane derivatives | ASTRAZENECA AB (SE) | 2002-12-10 | — | — | US | disclosed |