Acetylcysteine

Acetylcysteine

SCHEMBL5291

CC(=O)NC(CS)C(=O)O

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAPT P10636 2/20 1.00
KDM4E B2RXH2 1/20 1.00
THRB P10828 1/20 1.00
ALOX15 P16050 1/20 1.00
NFKB1 P19838 1/20 1.00
PTGS2 P35354 1/20 1.00
THPO P40225 1/20 1.00
RECQL P46063 1/20 1.00
BLM P54132 1/20 1.00
SMN1; SMN2 Q16637 1/20 1.00
ACE P12821 1/20 0.61
ALDH1A1 P00352 2/20 0.59
FOLH1 Q04609 3/20 0.52
CA1 P00915 2/20 0.41
CA2 P00918 2/20 0.41
GNPAT O15228 1/20 0.41
TGFBR1 P36897 1/20 0.41
NAALAD2 Q9Y3Q0 2/20 0.39
FNTA P49354 1/20 0.38
FNTB P49356 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Acetylcysteine SCHEMBL4433757 1.00 MAPT (1.00) MAPTKDM4ETHRBALOX15NFKB1
Acetylcysteine SCHEMBL3923962 1.00 MAPT (1.00) MAPTKDM4ETHRBALOX15NFKB1
Acetylcysteine SCHEMBL3923959 1.00 MAPT (1.00) MAPTKDM4ETHRBALOX15NFKB1
Acetylcysteine SCHEMBL4437350 1.00 MAPT (1.00) MAPTKDM4ETHRBALOX15NFKB1
Acetylcysteine SCHEMBL5292 1.00 MAPT (1.00) MAPTKDM4ETHRBALOX15NFKB1
Acetylcysteine SCHEMBL149212 1.00 MAPT (1.00) MAPTKDM4ETHRBALOX15NFKB1
Acetylcysteine SCHEMBL1384791 1.00 MAPT (1.00) MAPTKDM4ETHRBALOX15NFKB1
Acetylcysteine SCHEMBL3688241 1.00 MAPT (1.00) MAPTKDM4ETHRBALOX15NFKB1
Acetylcysteine SCHEMBL4437351 1.00 MAPT (1.00) MAPTKDM4ETHRBALOX15NFKB1
Acetylcysteine SCHEMBL4433756 1.00 MAPT (1.00) MAPTKDM4ETHRBALOX15NFKB1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Appears in 96132 patents — a generic fragment claimed broadly, so it's down-weighted as IP noise. Top by claim status then date:

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20260144744-A1 NASAL SPRAY SOLUTION FOR HANGOVERS AND METHOD FOR ITS PREPARATION Butura, Christian (US) 2026-05-28 US claimed
EP-4746864-A1 C5 KETONE COMPOSITIONS AND RELATED METHODS FOR TREATING METABOLIC DYSFUNCTION Keto Innovations, LLC (US) 2026-05-27 EP claimed
CN-122080093-A Compounds effective in treating liver toxicity and fatty liver disease and uses thereof 2026-05-26 CN claimed
CN-122075706-A Use of hyposulfonated glycogen synthase kinase-3 in the prevention and treatment of liver insulin resistance 2026-05-26 CN claimed
US-12636311-B2 Topically administered strontium-containing complexes for treating pain, pruritis and inflammation GALLEON LABS LLC (US) 2026-05-26 US claimed
US-12636282-B1 Therapeutic method against viral infection Feng, Helen (US) 2026-05-26 US claimed
CN-122081218-A Mesenchymal stem cell serum-free medium 2026-05-26 CN claimed
CN-122070903-A Liquid slow-release preparation 上海建毅腾创生物医药科技有限公司 2026-05-22 CN claimed
CN-122070813-A Copper doped nano magnesium hydroxide, preparation method and application 浙江新安化工集团股份有限公司 2026-05-22 CN claimed
WO-2026106919-A1 ENERGY BOOSTING AND MOBILITY INDUCING FORMULATION FOR ANIMALS INCLUDING PETS JONES MARGARET (US) 2026-05-21 WO claimed
US-4201694-A HIGH PH, MERCAPTAN, ALKYLENE POLYOL BECKMAN INSTRUMENTS, INC. (US) 1980-05-06 US claimed
EP-0006582-A2 Method for stabilizing solutions of gamma-glutamyl-p-nitroanilide Modrovich, Ivan Endre (US) 1980-01-09 EP claimed
US-4164570-A FOR TOPICAL TREATMENT OF GLAUCOMA CLOUGH DAVID (GB) 1979-08-14 US claimed
US-4150744-A Packaging SMITH & NEPHEW PHARMACEUTICALS LTD. (GB) 1979-04-24 US claimed
US-4139610-A CYSTEINE AND N-ACETYLCYSTEINE KYOWA HAKKO KOGYO KABUSHIKI KAISHA (JP) 1979-02-13 US claimed
US-4071517-A Soluble salts containing sulphur DUFOUR CLAUDE 1978-01-31 US claimed
US-4067775-A Process and composition for determining the activity of creatinekinase-MB MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DT) 1978-01-10 US claimed
US-4035349-A SULFHYDRYL AMINO ACIDS, ESTERS AND AMIDES, VEGETABLE PROTEIN THE UNITED STATES OF AMERICA AS REPRESENTED BY THE SECRETARY OF AGRICULTURE (US) 1977-07-12 US claimed
US-3966905-A POLYVINYL PYRROLIDONE BARNES-HIND PHARMACEUTICALS, INC. (US) 1976-06-29 US claimed
US-3934004-A Stain resistant anti-perspirant composition ORREN LEONARD J 1976-01-20 US claimed