Acetylcysteine

Acetylcysteine

SCHEMBL1384791

CC(=O)N[C@H](CS)C(=O)O

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAPT P10636 2/20 1.00
KDM4E B2RXH2 1/20 1.00
THRB P10828 1/20 1.00
ALOX15 P16050 1/20 1.00
NFKB1 P19838 1/20 1.00
PTGS2 P35354 1/20 1.00
THPO P40225 1/20 1.00
RECQL P46063 1/20 1.00
BLM P54132 1/20 1.00
SMN1; SMN2 Q16637 1/20 1.00
ACE P12821 1/20 0.61
ALDH1A1 P00352 2/20 0.59
FOLH1 Q04609 3/20 0.52
CA1 P00915 2/20 0.41
CA2 P00918 2/20 0.41
GNPAT O15228 1/20 0.41
TGFBR1 P36897 1/20 0.41
NAALAD2 Q9Y3Q0 2/20 0.39
FNTA P49354 1/20 0.38
FNTB P49356 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Acetylcysteine SCHEMBL4433757 1.00 MAPT (1.00) MAPTKDM4ETHRBALOX15NFKB1
Acetylcysteine SCHEMBL3923962 1.00 MAPT (1.00) MAPTKDM4ETHRBALOX15NFKB1
Acetylcysteine SCHEMBL3923959 1.00 MAPT (1.00) MAPTKDM4ETHRBALOX15NFKB1
Acetylcysteine SCHEMBL4437350 1.00 MAPT (1.00) MAPTKDM4ETHRBALOX15NFKB1
Acetylcysteine SCHEMBL5292 1.00 MAPT (1.00) MAPTKDM4ETHRBALOX15NFKB1
Acetylcysteine SCHEMBL149212 1.00 MAPT (1.00) MAPTKDM4ETHRBALOX15NFKB1
Acetylcysteine SCHEMBL3688241 1.00 MAPT (1.00) MAPTKDM4ETHRBALOX15NFKB1
Acetylcysteine SCHEMBL5291 1.00 MAPT (1.00) MAPTKDM4ETHRBALOX15NFKB1
Acetylcysteine SCHEMBL4437351 1.00 MAPT (1.00) MAPTKDM4ETHRBALOX15NFKB1
Acetylcysteine SCHEMBL4433756 1.00 MAPT (1.00) MAPTKDM4ETHRBALOX15NFKB1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 652 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-12636312-B2 Gold clusters (AuCs), composition and method for treatment of liver cirrhosis WUHAN VAST CONDUCT SCIENCE FOUNDATION CO., LTD. (CN) 2026-05-26 US claimed
US-12533378-B2 Treatment of adverse effects caused by atypical antipsychotics SHENZHEN PROFOUND VIEW PHARMACEUTICAL TECHNOLOGY CO., LTD. (CN) 2026-01-27 US claimed
US-12486178-B2 Copper nanoclusters, composition comprising the same, and treatment of multiple sclerosis Shenzhen Profound-View Pharma Tech Co., Ltd (CN) 2025-12-02 US claimed
US-20250249036-A1 Composition and Method for treatment of diabetes SHENZHEN PROFOUND VIEW PHARMACEUTICAL TECH CO LTD (CN) 2025-08-07 US claimed
US-12371339-B2 Copper nanoclusters, thymine-modified hyaluronic acid and poly(copper nanoclusters), method for preparing the same, and application thereof Shenzhen Profound-View Pharma Tech Co., Ltd (CN) 2025-07-29 US claimed
CN-120192252-A Synthesis method of key intermediate of itracin 安徽峆一药业股份有限公司 2025-06-24 CN claimed
US-12310985-B2 Composition and method for treatment of diabetes SHENZHEN PROFOUND VIEW PHARMACEUTICAL TECHNOLOGY (CN) 2025-05-27 US claimed
CN-119899242-A Method for producing AMG416 美国安进公司 2025-04-29 CN claimed
CN-119874825-A Method for producing AMG416 美国安进公司 2025-04-25 CN claimed
CN-114524860-B ETELCALCETIDE synthesis method and application thereof 深圳翰宇药业股份有限公司 2025-01-24 CN claimed
US-20040171682-A1 Drugs for chronic pains NICOX S.A. (FR) 2004-09-02 US claimed
US-20030141260-A1 Oxygen-enhanced pathogen inactivation GAMBRO, INC. 2003-07-31 US claimed
WO-2003057253-A1 OXYGEN-ENHANCED PATHOGEN INACTIVATION GAMBRO, INC. (US) 2003-07-17 WO claimed
CN-1424900-A Topical skin composition TONDAR COMMERCIAL GROUP INTERN (US) 2003-06-18 CN claimed
US-20030095959-A1 Topical skin composition ACCESS BUSINESS GROUP INTERNATIONAL LLC. 2003-05-22 US claimed
US-5728373-A EXHIBITING DEEP SKIN PENETRATION BEIERSDORF AG (DE) 1998-03-17 US claimed
WO-1997021423-A1 TOPICAL RETINOID COMPOSITION THE PROCTER & GAMBLE COMPANY (US) 1997-06-19 WO claimed
EP-0656774-B1 COSMETIC AND DERMATOLOGICAL SUNSCREEN COMPOSITIONS CONTAINING THIOLS AND/OR THIOL DERIVATES BEIERSDORF AG (DE) 1997-01-22 EP claimed
EP-0138262-B1 COMPOSITION FOR TREATMENT OF SKIN AFFECTIONS AND ITS APPLICATION Chemisch Adviesbureau Drs. J.C.P. Schreuder B.V. (NL) 1990-06-13 EP claimed
EP-0138262-A2 Composition for treatment of skin affections and its application Chemisch Adviesbureau Drs. J.C.P. Schreuder B.V. (NL) 1985-04-24 EP claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20040171682-A1 Drugs for chronic pains OPRD1, OPRK1, OPRL1 MAPT 1935/4885KDM4E 4186/4885THRB 1080/4885
US-12371339-B2 Copper nanoclusters, thymine-modified hyaluronic acid and poly(copper nanoclusters), method for preparing the same, and application thereof CD44, UMPS, CSGALNACT1 MAPT 1808/4885KDM4E 4754/4885THRB 846/4885
US-12533378-B2 Treatment of adverse effects caused by atypical antipsychotics FABP7, FABP4, LIPC MAPT 801/4885KDM4E 4588/4885THRB 75/4885
US-20030095959-A1 Topical skin composition CUTA, S100A4, KRT18 MAPT 1787/4885KDM4E 4634/4885THRB 3415/4885
US-12636312-B2 Gold clusters (AuCs), composition and method for treatment of liver cirrhosis FABP1, ALB, CSTB MAPT 2527/4885KDM4E 4638/4885THRB 699/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.