Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 8/20 | 1.00 |
| ▸ | NPC1 | O15118 | 6/20 | 1.00 |
| ▸ | SMN1; SMN2 | Q16637 | 6/20 | 1.00 |
| ▸ | KMT2A | Q03164 | 4/20 | 1.00 |
| ▸ | MEN1 | O00255 | 3/20 | 1.00 |
| ▸ | PAX8 | Q06710 | 2/20 | 1.00 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 1.00 |
| ▸ | PKM | P14618 | 1/20 | 1.00 |
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.61 |
| ▸ | MAPT | P10636 | 3/20 | 0.54 |
| ▸ | HPGD | P15428 | 3/20 | 0.54 |
| ▸ | GLA | P06280 | 2/20 | 0.54 |
| ▸ | LMNA | P02545 | 2/20 | 0.54 |
| ▸ | TP53 | P04637 | 1/20 | 0.54 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.54 |
| ▸ | CASP3 | P42574 | 1/20 | 0.54 |
| ▸ | CCR6 | P51684 | 1/20 | 0.54 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.54 |
| ▸ | RELA | Q04206 | 1/20 | 0.54 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15246728 | 0.74 | MEN1 (0.59) | RAB9ANPC1SMN1; SMN2KMT2AMEN1 | |
| SCHEMBL21295 | 0.71 | KMT2A (0.70) | RAB9ANPC1SMN1; SMN2KMT2AMEN1 | |
| SCHEMBL29668346 | 0.71 | KMT2A (0.70) | RAB9ANPC1SMN1; SMN2KMT2AMEN1 | |
| SCHEMBL14917566 | 0.71 | RAB9A (0.76) | RAB9ANPC1SMN1; SMN2KMT2AMEN1 | |
| SCHEMBL2252028 | 0.70 | SMN1; SMN2 (1.00) | RAB9ANPC1SMN1; SMN2KMT2AMEN1 | |
| SCHEMBL14041423 | 0.70 | MAPT (0.73) | RAB9ANPC1SMN1; SMN2KMT2AMEN1 | |
| SCHEMBL27869264 | 0.70 | KDM4E (0.56) | RAB9ANPC1SMN1; SMN2KMT2AMEN1 | |
| SCHEMBL15246706 | 0.69 | ALKBH3 (0.58) | RAB9ANPC1SMN1; SMN2KMT2AMEN1 | |
| SCHEMBL16387688 | 0.69 | MAPT (0.62) | RAB9ANPC1SMN1; SMN2KMT2AMEN1 | |
| SCHEMBL5916780 | 0.69 | KDM4E (0.53) | RAB9ANPC1SMN1; SMN2KMT2AMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007002587-A2 | INHIBITORS OF EPSTEIN BARR VIRUS NUCLEAR ANTIGEN 1 | THE BRIGHAM AND WOMEN'S HOSPITAL, INC. (US) | 2007-01-04 | — | — | WO | claimed |
| WO-2007002587-A2 | INHIBITORS OF EPSTEIN BARR VIRUS NUCLEAR ANTIGEN 1 | THE BRIGHAM AND WOMEN'S HOSPITAL, INC. (US) | 2007-01-04 | — | — | WO | disclosed |