Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DGAT1 | O75907 | 20/20 | 0.80 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3541491 | 0.90 | DGAT1 (1.00) | DGAT1 | |
| SCHEMBL5308194 | 0.89 | DGAT1 (0.67) | DGAT1 | |
| SCHEMBL3544242 | 0.84 | DGAT1 (0.85) | DGAT1 | |
| SCHEMBL3539845 | 0.83 | DGAT1 (1.00) | DGAT1 | |
| SCHEMBL3540480 | 0.82 | DGAT1 (0.81) | DGAT1 | |
| SCHEMBL3537813 | 0.81 | DGAT1 (1.00) | DGAT1 | |
| SCHEMBL3547198 | 0.81 | DGAT1 (0.82) | DGAT1 | |
| SCHEMBL3542950 | 0.81 | DGAT1 (0.79) | DGAT1 | |
| SCHEMBL3543868 | 0.79 | DGAT1 (1.00) | DGAT1 | |
| SCHEMBL3541703 | 0.78 | DGAT1 (0.74) | DGAT1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1833806-A1 | OXADIAZOLE DERIVATIVES AS DGAT INHIBITORS | AstraZeneca AB (SE) | 2007-09-19 | — | — | EP | disclosed |
| WO-2006064189-A1 | OXADIAZOLE DERIVATIVES AS DGAT INHIBITORS | ASTRAZENECA AB (SE) | 2006-06-22 | — | — | WO | disclosed |