Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TLR2 | O60603 | 3/20 | 0.56 |
| ▸ | TLR1 | Q15399 | 3/20 | 0.56 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.53 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.53 |
| ▸ | KDM1A | O60341 | 13/20 | 0.50 |
| ▸ | MAOB | P27338 | 7/20 | 0.50 |
| ▸ | MAOA | P21397 | 4/20 | 0.50 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.46 |
| ▸ | RCOR1 | Q9UKL0 | 2/20 | 0.46 |
| ▸ | KDM1B | Q8NB78 | 1/20 | 0.46 |
| ▸ | CNR1 | P21554 | 1/20 | 0.43 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL529661 | 1.00 | TLR2 (0.56) | TLR2TLR1SMN1; SMN2NPSR1KDM1A | |
| SCHEMBL2562813 | 1.00 | TLR2 (0.56) | TLR2TLR1SMN1; SMN2NPSR1KDM1A | |
| SCHEMBL11888836 | 0.84 | KDM1A (0.63) | KDM1AMAOBMAOA | |
| SCHEMBL11888872 | 0.84 | SMN1; SMN2 (0.54) | TLR2TLR1SMN1; SMN2NPSR1KDM1A | |
| SCHEMBL11888871 | 0.84 | SMN1; SMN2 (0.54) | TLR2TLR1SMN1; SMN2NPSR1KDM1A | |
| SCHEMBL7980208 | 0.83 | SMN1; SMN2 (0.73) | TLR2TLR1SMN1; SMN2NPSR1KDM1A | |
| SCHEMBL6153775 | 0.83 | SMN1; SMN2 (0.73) | TLR2TLR1SMN1; SMN2NPSR1KDM1A | |
| SCHEMBL6154005 | 0.83 | SMN1; SMN2 (0.73) | TLR2TLR1SMN1; SMN2NPSR1KDM1A | |
| SCHEMBL3457343 | 0.83 | SMN1; SMN2 (0.73) | TLR2TLR1SMN1; SMN2NPSR1KDM1A | |
| SCHEMBL19357558 | 0.83 | KDM1A (0.65) | KDM1AMAOBMAOARCOR1KDM1B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2598482-A1 | ARYLCYCLOPROPYLAMINE BASED DEMETHYLASE INHIBITORS OF LSD1 AND THEIR MEDICAL USE | Oryzon Genomics, S.A. (ES) | 2013-06-05 | — | — | EP | disclosed |
| WO-2012013728-A1 | ARYLCYCLOPROPYLAMINE BASED DEMETHYLASE INHIBITORS OF LSD1 AND THEIR MEDICAL USE | ORYZON GENOMICS S.A. (ES) | 2012-02-02 | — | — | WO | disclosed |