SCHEMBL5296934

SCHEMBL5296934

CN1C=CN(Cc2ccccc2)C1Cc1ccccc1

nearest known ligand 0.43

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
CCR3 P51677 1/20 0.39
MC4R P32245 1/20 0.38
EP300 Q09472 1/20 0.38
CARM1 Q86X55 2/20 0.36
PRMT6 Q96LA8 2/20 0.36
ACHE P22303 1/20 0.36
PRMT3 O60678 1/20 0.36
PRMT1 Q99873 1/20 0.36
PRMT8 Q9NR22 1/20 0.36
SIGMAR1 Q99720 1/20 0.35
ALDH1A1 P00352 1/20 0.35
LMNA P02545 1/20 0.35
NPSR1 Q6W5P4 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5299826 0.86 MC4R (0.38) MC4RACHESIGMAR1ALDH1A1LMNA
SCHEMBL5285508 0.86 PRMT6 (0.36) CARM1PRMT6PRMT3PRMT1PRMT8
SCHEMBL1836403 0.85 CARM1 (0.42) CCR3CARM1PRMT6PRMT3PRMT1
SCHEMBL5289117 0.84 KCNH2 (0.38) CARM1PRMT6PRMT3PRMT1PRMT8
Hydrochloric Acid SCHEMBL20263714 0.84 MC4R (0.37) MC4RACHESIGMAR1ALDH1A1LMNA
SCHEMBL5296151 0.83 KCNH2 (0.37) CCR3MC4REP300
SCHEMBL5303731 0.83 KMT2A (0.38) MC4RACHESIGMAR1
SCHEMBL5304168 0.82 CCR3 (0.39) CCR3MC4REP300ACHESIGMAR1
SCHEMBL5295730 0.81 KCNH2 (0.42)
SCHEMBL5295692 0.80 KCNH2 (0.48)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2007006418-A1 IONIC-LIQUID-CONTAINING PRODUCTS FOR DYEING AND/OR BRIGHTENING KERATIN FIBRES HENKEL KOMMANDITGESELLSCHAFT AUF AKTIEN (DE) 2007-01-18 WO disclosed
WO-2006131234-A1 COSMETIC COMPOSITIONS COMPRISING IONIC LIQUIDS HENKEL KOMMANDITGESELLSCHAFT AUF AKTIEN (DE) 2006-12-14 WO disclosed