Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 2/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.39 |
| ▸ | TXNRD1 | Q16881 | 1/20 | 0.39 |
| ▸ | TXNRD3 | Q86VQ6 | 1/20 | 0.39 |
| ▸ | TXNRD2 | Q9NNW7 | 1/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | ABCC8 | Q09428 | 1/20 | 0.39 |
| ▸ | KCNJ11 | Q14654 | 1/20 | 0.39 |
| ▸ | HPD | P32754 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 4/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.38 |
| ▸ | TDO2 | P48775 | 2/20 | 0.38 |
| ▸ | IDO1 | P14902 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 2/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14610390 | 0.78 | GAA (0.42) | GAAALDH1A1CYP3A4HPGDALOX15 | |
| SCHEMBL9057515 | 0.77 | AR (0.50) | ALDH1A1HPGDTSHRKDM4ETDO2 | |
| SCHEMBL8003279 | 0.74 | ALDH1A1 (0.49) | GAAALDH1A1CYP3A4HPGDALOX15 | |
| SCHEMBL13678600 | 0.73 | MAPK1 (0.53) | GAAALDH1A1CYP3A4HPGDALOX15 | |
| SCHEMBL258621 | 0.72 | ALDH1A1 (0.50) | GAAALDH1A1CYP3A4HPGDALOX15 | |
| SCHEMBL148988 | 0.72 | ALDH1A1 (0.50) | GAAALDH1A1CYP3A4HPGDALOX15 | |
| SCHEMBL5458551 | 0.72 | ALDH1A1 (0.50) | GAAALDH1A1CYP3A4HPGDALOX15 | |
| SCHEMBL2923553 | 0.72 | ALDH1A1 (0.50) | GAAALDH1A1CYP3A4HPGDALOX15 | |
| SCHEMBL31672179 | 0.72 | ALDH1A1 (0.50) | GAAALDH1A1CYP3A4HPGDALOX15 | |
| SCHEMBL5237815 | 0.72 | ALDH1A1 (0.50) | GAAALDH1A1CYP3A4HPGDALOX15 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007014054-A2 | BENZENESULFONAMIDE INHIBITOR OF CCR2 CHEMOKINE RECEPTOR | GLAXO GROUP LIMTED (GB) | 2007-02-01 | — | — | WO | disclosed |