SCHEMBL529792

SCHEMBL529792

C=CCOCC(O)CNc1ccc(Nc2ccccc2)cc1

nearest known ligand 0.54

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAPT P10636 5/20 0.54
HTT P42858 2/20 0.52
SMN1; SMN2 Q16637 1/20 0.52
ADRB1 P08588 2/20 0.41
ADRB3 P13945 1/20 0.41
CA1 P00915 1/20 0.41
CA2 P00918 1/20 0.41
CA7 P43166 1/20 0.41
CYP2D6 P10635 3/20 0.41
SLC22A1 O15245 1/20 0.41
LMNA P02545 1/20 0.41
CYP1A2 P05177 1/20 0.41
ADRB2 P07550 1/20 0.41
HTR1A P08908 1/20 0.41
HTR2A P28223 1/20 0.41
SLC6A4 P31645 1/20 0.41
ADRA1A P35348 1/20 0.41
DNM1 Q05193 1/20 0.40
ABCB1 P08183 2/20 0.39
TLR4 O00206 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL529794 0.86 MAPT (0.44) MAPTHTTSMN1; SMN2ADRB1ADRB3
SCHEMBL3083090 0.84 MAPT (0.55) MAPTHTTSMN1; SMN2ADRB1ADRB3
SCHEMBL11032147 0.82 MAPT (0.45) MAPTHTTSMN1; SMN2ADRB1ADRB3
SCHEMBL3083085 0.81 MAPT (0.57) MAPTHTTSMN1; SMN2ADRB1ADRB3
SCHEMBL11648049 0.78 MAPT (0.51) MAPTHTTSMN1; SMN2ADRB1ADRB3
SCHEMBL11035611 0.78 CA1 (0.48) MAPTHTTSMN1; SMN2ADRB1ADRB3
SCHEMBL13838308 0.78 MAPT (0.59) MAPTHTTSMN1; SMN2ADRB1ADRB3
SCHEMBL11035087 0.78 FFAR1 (0.55) MAPTHTTSMN1; SMN2ADRB1ADRB3
SCHEMBL3393717 0.77 MAPT (0.56) MAPTHTTSMN1; SMN2ADRB1ADRB3
SCHEMBL11602854 0.77 MAPT (0.88) MAPTHTTSMN1; SMN2ADRB1ADRB3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 24 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-4806447-A Method of chemically bonding antioxidants into polymeric materials THE GOODYEAR TIRE & RUBBER COMPANY (US) 1989-02-21 US claimed
US-4739014-A USING FREE RADICAL CATALYST THE GOODYEAR TIRE & RUBBER COMPANY (US) 1988-04-19 US claimed
JP-54062246-A None JP disclosed
EP-2222910-B1 ENVIRONMENTALLY RESISTANT BALLISTIC COMPOSITE BASED ON A NITRILE RUBBER BINDER HONEYWELL INT INC (US) 2015-08-26 EP disclosed
EP-2598825-A2 BALLISTIC SHIELD COMPOSITES WITH ENHANCED FRAGMENT RESISTANCE Honeywell International, Inc. (US) 2013-06-05 EP disclosed
US-8158540-B2 Environmentally resistant ballistic composite based on a nitrile rubber binder HONEYWELL INTERNATIONAL INC. (US) 2012-04-17 US disclosed
WO-2012015680-A2 BALLISTIC SHIELD COMPOSITES WITH ENHANCED FRAGMENT RESISTANCE HONEYWELL INTERNATIONAL INC. (US) 2012-02-02 WO disclosed
US-8080486-B1 Ballistic shield composites with enhanced fragment resistance HONEYWELL INTERNATIONAL INC. (US) 2011-12-20 US disclosed
US-20110143086-A1 ENVIRONMENTALLY RESISTANT BALLISTIC COMPOSITE BASED ON A NITRILE RUBBER BINDER HONEYWELL INTERNATIONAL INC. (US) 2011-06-16 US disclosed
US-7858540-B2 Environmentally resistant ballistic composite based on a nitrile rubber binder HONEYWELL INTERNATIONAL INC. (US) 2010-12-28 US disclosed
EP-2222910-A2 ENVIRONMENTALLY RESISTANT BALLISTIC COMPOSITE BASED ON A NITRILE RUBBER BINDER Honeywell International Inc. (US) 2010-09-01 EP disclosed
EP-0747458-B1 Adhesive composition and composite of rubber with fiber NIPPON ZEON CO (JP) 1999-03-31 EP disclosed
US-5861212-A LATEX OF CARBOXYLATED HIGHLY SATURATED NITRILE-CONJUGATED DIENE COPOLYMER RUBBER, RESORCINOL-FORMALDEHYDE RESIN, AND AROMATIC EPOXY RESIN; BELTS NIPPON ZEON CO., LTD. (JP) 1999-01-19 US disclosed
US-5783625-A SELF-CROSSLINKING LATEX CONTAINING HYDROGENATED RUBBER COPOLYMERS OF UNSATURATED NITRILES, CARBOXYLIC ACIDS AND CONJUGATED DIENES BLENDED WITH RESORCINOL-FORMALDEHYDE RESIN, FOR BONDING TO FABRICS, ABRASION, WATER AND HEAT RESISTANCE NIPPON ZEON CO., LTD. (JP) 1998-07-21 US disclosed
EP-0704508-B1 Adhesive composition and composite of rubber with fiber NIPPON ZEON CO (JP) 1997-09-17 EP disclosed
EP-0747458-A1 Adhesive composition and composite of rubber with fiber NIPPON ZEON CO., LTD. (JP) 1996-12-11 EP disclosed
EP-0704508-A1 Adhesive composition and composite of rubber with fiber NIPPON ZEON CO., LTD. (JP) 1996-04-03 EP disclosed
US-4806447-A Method of chemically bonding antioxidants into polymeric materials THE GOODYEAR TIRE & RUBBER COMPANY (US) 1989-02-21 US disclosed
US-4739014-A USING FREE RADICAL CATALYST THE GOODYEAR TIRE & RUBBER COMPANY (US) 1988-04-19 US disclosed
JP-S5462246-A DETERIORATION INHIBITOR FOR RUBBER NIPPON ZEON CO LTD 1979-05-19 JP disclosed