SCHEMBL529794

SCHEMBL529794

C=CCOCC(O)CNc1ccccc1Nc1ccccc1

nearest known ligand 0.44

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAPT P10636 3/20 0.44
HTT P42858 1/20 0.43
SMN1; SMN2 Q16637 1/20 0.43
ADRB1 P08588 4/20 0.40
CYP2D6 P10635 3/20 0.40
ADRB2 P07550 3/20 0.40
LMNA P02545 2/20 0.40
HTR1A P08908 2/20 0.40
SLC6A4 P31645 2/20 0.40
ADRA1A P35348 2/20 0.40
SLC22A1 O15245 1/20 0.40
CYP1A2 P05177 1/20 0.40
HTR2A P28223 1/20 0.40
CA1 P00915 2/20 0.40
CA2 P00918 2/20 0.40
CA7 P43166 2/20 0.40
ADRB3 P13945 3/20 0.35
CA4 P22748 1/20 0.35
CA9 Q16790 1/20 0.35
ALDH1A1 P00352 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL529792 0.86 MAPT (0.54) MAPTHTTSMN1; SMN2ADRB1CYP2D6
SCHEMBL530315 0.82 MAPT (0.48) MAPTHTTSMN1; SMN2ADRB1CYP2D6
SCHEMBL11033804 0.81 ALDH1A1 (0.43) MAPTSMN1; SMN2ADRB1CYP2D6ADRB2
SCHEMBL11328310 0.79 BACE1 (0.52) MAPTSMN1; SMN2ADRB1CYP2D6ADRB2
SCHEMBL11147759 0.77 CA1 (0.41) MAPTHTTSMN1; SMN2ADRB1CYP2D6
SCHEMBL529793 0.74 MAPT (0.50) MAPTHTTSMN1; SMN2ADRB1CYP2D6
SCHEMBL11035087 0.73 FFAR1 (0.55) MAPTHTTSMN1; SMN2ADRB1ADRB2
SCHEMBL11032147 0.72 MAPT (0.45) MAPTHTTSMN1; SMN2ADRB1ADRB2
SCHEMBL3083090 0.71 MAPT (0.55) MAPTHTTSMN1; SMN2ADRB1CYP2D6
SCHEMBL22584879 0.70 MAPT (0.47) MAPTHTTSMN1; SMN2ADRB1CYP2D6

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 18 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2222910-B1 ENVIRONMENTALLY RESISTANT BALLISTIC COMPOSITE BASED ON A NITRILE RUBBER BINDER HONEYWELL INT INC (US) 2015-08-26 EP disclosed
EP-2598825-A2 BALLISTIC SHIELD COMPOSITES WITH ENHANCED FRAGMENT RESISTANCE Honeywell International, Inc. (US) 2013-06-05 EP disclosed
CN-101952499-B Environmentally resistant ballistic composites based on nitrile rubber binders HONEYWELL INT INC 2012-08-29 CN disclosed
US-8158540-B2 Environmentally resistant ballistic composite based on a nitrile rubber binder HONEYWELL INTERNATIONAL INC. (US) 2012-04-17 US disclosed
WO-2012015680-A2 BALLISTIC SHIELD COMPOSITES WITH ENHANCED FRAGMENT RESISTANCE HONEYWELL INTERNATIONAL INC. (US) 2012-02-02 WO disclosed
US-8080486-B1 Ballistic shield composites with enhanced fragment resistance HONEYWELL INTERNATIONAL INC. (US) 2011-12-20 US disclosed
US-20110143086-A1 ENVIRONMENTALLY RESISTANT BALLISTIC COMPOSITE BASED ON A NITRILE RUBBER BINDER HONEYWELL INTERNATIONAL INC. (US) 2011-06-16 US disclosed
CN-101952499-A Environmentally resistant ballistic composites based on nitrile rubber binders HONEYWELL INT INC 2011-01-19 CN disclosed
US-7858540-B2 Environmentally resistant ballistic composite based on a nitrile rubber binder HONEYWELL INTERNATIONAL INC. (US) 2010-12-28 US disclosed
EP-2222910-A2 ENVIRONMENTALLY RESISTANT BALLISTIC COMPOSITE BASED ON A NITRILE RUBBER BINDER Honeywell International Inc. (US) 2010-09-01 EP disclosed
WO-2009085674-A2 ENVIRONMENTALLY RESISTANT BALLISTIC COMPOSITE BASED ON A NITRILE RUBBER BINDER HONEYWELL INTERNATIONAL INC. (US) 2009-07-09 WO disclosed
US-20090163105-A1 Environmentally Resistant Ballistic Composite Based on a Nitrile Rubber Binder SOLSTICE ADVANCED MATERIALS US, INC. 2009-06-25 US disclosed
EP-0747458-B1 Adhesive composition and composite of rubber with fiber NIPPON ZEON CO (JP) 1999-03-31 EP disclosed
US-5861212-A LATEX OF CARBOXYLATED HIGHLY SATURATED NITRILE-CONJUGATED DIENE COPOLYMER RUBBER, RESORCINOL-FORMALDEHYDE RESIN, AND AROMATIC EPOXY RESIN; BELTS NIPPON ZEON CO., LTD. (JP) 1999-01-19 US disclosed
US-5783625-A SELF-CROSSLINKING LATEX CONTAINING HYDROGENATED RUBBER COPOLYMERS OF UNSATURATED NITRILES, CARBOXYLIC ACIDS AND CONJUGATED DIENES BLENDED WITH RESORCINOL-FORMALDEHYDE RESIN, FOR BONDING TO FABRICS, ABRASION, WATER AND HEAT RESISTANCE NIPPON ZEON CO., LTD. (JP) 1998-07-21 US disclosed
EP-0704508-B1 Adhesive composition and composite of rubber with fiber NIPPON ZEON CO (JP) 1997-09-17 EP disclosed
EP-0747458-A1 Adhesive composition and composite of rubber with fiber NIPPON ZEON CO., LTD. (JP) 1996-12-11 EP disclosed
EP-0704508-A1 Adhesive composition and composite of rubber with fiber NIPPON ZEON CO., LTD. (JP) 1996-04-03 EP disclosed