Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CCR1 | P32246 | 1/20 | 0.39 |
| ▸ | CCR2 | P41597 | 1/20 | 0.39 |
| ▸ | CCR4 | P51679 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | CYP19A1 | P11511 | 3/20 | 0.34 |
| ▸ | CD44 | P16070 | 1/20 | 0.30 |
| ▸ | FLT1 | P17948 | 1/20 | 0.30 |
| ▸ | AHR | P35869 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14610754 | 0.72 | CYP19A1 (0.46) | CCR1CCR2CCR4CYP19A1 | |
| SCHEMBL14610530 | 0.72 | CCR1 (0.49) | CCR1CCR2CCR4CYP19A1 | |
| SCHEMBL14610826 | 0.70 | CCR1 (0.40) | CCR1CCR2CCR4 | |
| SCHEMBL27895858 | 0.68 | GAA (0.48) | GAACD44FLT1AHR | |
| SCHEMBL5306461 | 0.67 | SMN1; SMN2 (0.56) | CCR1CCR2CCR4CYP19A1 | |
| SCHEMBL16181881 | 0.66 | GAA (0.46) | GAACD44FLT1AHR | |
| SCHEMBL12963082 | 0.66 | GAA (0.46) | GAACD44 | |
| SCHEMBL28962613 | 0.63 | HTT (0.57) | GAA | |
| SCHEMBL30216869 | 0.63 | HTT (0.57) | GAA | |
| SCHEMBL14322800 | 0.63 | CYP11B1 (0.60) | CYP19A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007014054-A2 | BENZENESULFONAMIDE INHIBITOR OF CCR2 CHEMOKINE RECEPTOR | GLAXO GROUP LIMTED (GB) | 2007-02-01 | — | — | WO | disclosed |
| WO-2007014054-A2 | BENZENESULFONAMIDE INHIBITOR OF CCR2 CHEMOKINE RECEPTOR | GLAXO GROUP LIMTED (GB) | 2007-02-01 | — | — | WO | disclosed |