Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP19A1 | P11511 | 11/20 | 0.46 |
| ▸ | CCR1 | P32246 | 1/20 | 0.43 |
| ▸ | CCR2 | P41597 | 1/20 | 0.43 |
| ▸ | CCR4 | P51679 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | STS | P08842 | 2/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | PKM | P14618 | 1/20 | 0.38 |
| ▸ | BRD4 | O60885 | 1/20 | 0.38 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.37 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7445529 | 0.81 | CCR1 (0.50) | CYP19A1CCR1CCR2CCR4MEN1 | |
| SCHEMBL31005994 | 0.74 | CYP19A1 (0.44) | CYP19A1STSBRD4HDAC1HDAC6 | |
| SCHEMBL5305019 | 0.74 | CCR1 (0.45) | CYP19A1CCR1CCR2CCR4MEN1 | |
| SCHEMBL9747728 | 0.73 | CCR1 (0.55) | CYP19A1CCR1CCR2CCR4MEN1 | |
| SCHEMBL19566595 | 0.72 | CYP19A1 (0.58) | CYP19A1BRD4HDAC1HDAC6 | |
| SCHEMBL940881 | 0.72 | CYP19A1 (0.62) | CYP19A1CCR1CCR2CCR4MEN1 | |
| SCHEMBL5300097 | 0.72 | CCR1 (0.39) | CYP19A1CCR1CCR2CCR4 | |
| SCHEMBL5306457 | 0.71 | CYP19A1 (0.61) | CYP19A1CCR1CCR2CCR4MEN1 | |
| Hydrochloric Acid SCHEMBL11356117 | 0.71 | CYP19A1 (0.61) | CYP19A1CCR1CCR2CCR4MEN1 | |
| SCHEMBL14610530 | 0.70 | CCR1 (0.49) | CYP19A1CCR1CCR2CCR4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007014054-A2 | BENZENESULFONAMIDE INHIBITOR OF CCR2 CHEMOKINE RECEPTOR | GLAXO GROUP LIMTED (GB) | 2007-02-01 | — | — | WO | disclosed |