Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A3 | P47895 | 6/20 | 0.61 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.61 |
| ▸ | NPC1 | O15118 | 8/20 | 0.60 |
| ▸ | RAB9A | P51151 | 8/20 | 0.60 |
| ▸ | SCD | O00767 | 1/20 | 0.60 |
| ▸ | TLR9 | Q9NR96 | 1/20 | 0.58 |
| ▸ | ALDH1A2 | O94788 | 2/20 | 0.57 |
| ▸ | TP53 | P04637 | 1/20 | 0.53 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.53 |
| ▸ | SLC2A1 | P11166 | 1/20 | 0.51 |
| ▸ | PLK4 | O00444 | 1/20 | 0.50 |
| ▸ | JAK2 | O60674 | 1/20 | 0.50 |
| ▸ | RET | P07949 | 1/20 | 0.50 |
| ▸ | PIM1 | P11309 | 1/20 | 0.50 |
| ▸ | FGFR1 | P11362 | 1/20 | 0.50 |
| ▸ | FLT1 | P17948 | 1/20 | 0.50 |
| ▸ | KDR | P35968 | 1/20 | 0.50 |
| ▸ | FLT3 | P36888 | 1/20 | 0.50 |
| ▸ | PIM3 | Q86V86 | 1/20 | 0.50 |
| ▸ | ALK | Q9UM73 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28396792 | 0.97 | TLR9 (0.61) | ALDH1A3ALDH1A1NPC1RAB9ASCD | |
| SCHEMBL1691462 | 0.89 | RAB9A (0.66) | ALDH1A3ALDH1A1NPC1RAB9ASCD | |
| SCHEMBL13325781 | 0.85 | SCD (0.65) | ALDH1A3ALDH1A1NPC1RAB9ASCD | |
| SCHEMBL22907197 | 0.84 | SMN1; SMN2 (0.74) | ALDH1A3ALDH1A1NPC1RAB9ASCD | |
| SCHEMBL2511536 | 0.84 | NPC1 (0.68) | ALDH1A3ALDH1A1NPC1RAB9ASCD | |
| SCHEMBL13325776 | 0.83 | TLR9 (0.65) | ALDH1A3ALDH1A1NPC1RAB9ASCD | |
| Bromide SCHEMBL1691791 | 0.83 | NPC1 (0.67) | ALDH1A3ALDH1A1NPC1RAB9ASCD | |
| SCHEMBL13325899 | 0.81 | SMN1; SMN2 (0.79) | ALDH1A3ALDH1A1NPC1RAB9ASCD | |
| SCHEMBL13325729 | 0.81 | NPC1 (0.72) | ALDH1A3ALDH1A1NPC1RAB9ATLR9 | |
| SCHEMBL25790043 | 0.81 | RAB9A (0.73) | ALDH1A3ALDH1A1NPC1RAB9AALDH1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007034282-A2 | DIARYL-IMIDAZOLE COMPOUNDS CONDENSED WITH A HETEROCYCLE AS C3A RECEPTOR ANTAGONISTS | PFIZER PRODUCTS INC. (US) | 2007-03-29 | — | — | WO | disclosed |