Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | CXCR4 | P61073 | 1/20 | 0.35 |
| ▸ | TGFBR1 | P36897 | 1/20 | 0.34 |
| ▸ | TLR7 | Q9NYK1 | 3/20 | 0.33 |
| ▸ | CA2 | P00918 | 2/20 | 0.32 |
| ▸ | POLB | P06746 | 1/20 | 0.32 |
| ▸ | TLR8 | Q9NR97 | 1/20 | 0.31 |
| ▸ | TBXAS1 | P24557 | 1/20 | 0.30 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.30 |
| ▸ | HRH1 | P35367 | 1/20 | 0.30 |
| ▸ | CYP4F2 | P78329 | 1/20 | 0.30 |
| ▸ | CYP4A11 | Q02928 | 1/20 | 0.30 |
| ▸ | LOX | P28300 | 1/20 | 0.30 |
| ▸ | AOC3 | Q16853 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5306179 | 0.85 | CYP2D6 (0.32) | POLBCYP2D6HRH1 | |
| SCHEMBL30803975 | 0.85 | CYP2D6 (0.32) | POLBCYP2D6HRH1 | |
| SCHEMBL293479 | 0.81 | TDP1 (0.41) | KDM4ETLR7POLBCYP2D6 | |
| SCHEMBL30665021 | 0.81 | TDP1 (0.41) | KDM4ETLR7POLBCYP2D6 | |
| SCHEMBL10836044 | 0.79 | CYP2D6 (0.35) | CYP2D6HRH1 | |
| SCHEMBL10496018 | 0.79 | TDP1 (0.40) | KDM4ETLR7TBXAS1 | |
| SCHEMBL293872 | 0.78 | HRH3 (0.36) | TGFBR1CA2POLBCYP2D6 | |
| Ethoxycarbonyl Group SCHEMBL27894069 | 0.77 | CYP4F2 (0.31) | CXCR4CYP4F2CYP4A11 | |
| SCHEMBL30901844 | 0.77 | CYP2D6 (0.33) | CYP2D6HRH1 | |
| SCHEMBL7356709 | 0.75 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10271573-B2 | Tobacco with an increased level of natural tar diluents | PHILIP MORRIS USA INC. (US) | 2019-04-30 | — | — | US | claimed |
| WO-2007012980-A1 | TOBACCO WITH AN INCREASED LEVEL OF NATURAL TAR DILUTENTS | PHILIP MORRIS PRODUCTS S.A. (CH) | 2007-02-01 | — | — | WO | claimed |
| US-20060283469-A1 | Tobacco with an increased level of natural tar diluents | PHILIP MORRIS USA INC. (US) | 2006-12-21 | — | — | US | claimed |
| US-10271573-B2 | Tobacco with an increased level of natural tar diluents | PHILIP MORRIS USA INC. (US) | 2019-04-30 | — | — | US | disclosed |
| WO-2007012980-A1 | TOBACCO WITH AN INCREASED LEVEL OF NATURAL TAR DILUTENTS | PHILIP MORRIS PRODUCTS S.A. (CH) | 2007-02-01 | — | — | WO | disclosed |
| US-20060283469-A1 | Tobacco with an increased level of natural tar diluents | PHILIP MORRIS USA INC. (US) | 2006-12-21 | — | — | US | disclosed |